The proximate mechanisms by which physical activity (PA) slows senescence and
decreases morbidity and mortality have been extensively documented. However, we lack an …

According to life history theory, increased investment in reproductive function (physiology
and behaviour) at different times throughout the life course affects the risk of many diseases …

Life history theory seeks to explain the evolution of the major features of life cycles by
analyzing the ecological factors that shape age-specific schedules of growth, reproduction …

Western lifestyles differ markedly from those of our hunter-gatherer ancestors, and these
differences in diet and activity level are often implicated in the global obesity pandemic …

Natural selection favors the optimal allocation of energy and other limiting resources to
reproduction. Human reproductive physiology displays characteristic patterns that can be …

Recent advances in human life history theory have provided new insights into the potential
selection pressures that were instrumental in the evolution of human and non‐human …

Sickness behavior, a coordinated set of behavioral changes in response to infection, lies at
the intersection of immunology, endocrinology, and evolutionary biology. Sickness behavior …

Despite recent rapid advances in medical knowledge that have improved survival,
conventional medical science's understanding of human health and disease relies heavily …

The human body adapts dynamically to maintain total energy expenditure (TEE) within a
narrow physiological range. Rather than increasing with physical activity in a dose …

We hypothesize that, ancestrally, sex-specific immune modulation evolved to facilitate
survival of the pregnant person in the presence of an invasive placenta and an …