Regulatory functions of hypoxia in host–parasite interactions: a focus on enteric, tissue, and blood protozoa
Body tissues are subjected to various oxygenic gradients and fluctuations and hence can
become transiently hypoxic. Hypoxia-inducible factor (HIF) is the master transcriptional …
become transiently hypoxic. Hypoxia-inducible factor (HIF) is the master transcriptional …
Understanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory
Plasmodium falciparum undergoes sequestration within deep tissues of the human body,
spanning multiple organ systems with differing oxygen (O2) concentrations. The parasite is …
spanning multiple organ systems with differing oxygen (O2) concentrations. The parasite is …
LPS-mediated neutrophil VEGF-A release is modulated by cannabinoid receptor activation
M Braile, L Cristinziano, S Marcella… - Journal of Leucocyte …, 2021 - academic.oup.com
Neutrophils (PMNs) are innate immune cells with primary roles in inflammation and in host
defense against infections. Both inflammatory and tumor angiogenesis are modulated by a …
defense against infections. Both inflammatory and tumor angiogenesis are modulated by a …
Gardnerella vaginalis infection in pregnancy: Effects on placental development and neonatal outcomes
Introduction Gardnerella vaginalis (GV)-associated bacterial vaginosis is recognised for its
detrimental effects on pregnancy resulting in poor obstetric and neonatal outcomes. There is …
detrimental effects on pregnancy resulting in poor obstetric and neonatal outcomes. There is …
Altered Cytokine Response of Human Brain Endothelial Cells after Stimulation with Malaria Patient Plasma
M Raacke, A Kerr, M Dörpinghaus, J Brehmer, Y Wu… - Cells, 2021 - mdpi.com
Infections with the deadliest malaria parasite, Plasmodium falciparum, are accompanied by
a strong immunological response of the human host. To date, more than 30 cytokines have …
a strong immunological response of the human host. To date, more than 30 cytokines have …
Hypoxia and collagen deposition in the kidneys infected with Acanthamoeba sp.
K Kot, M Grabowska, M Tarnowski, P Kupnicka… - Scientific Reports, 2024 - nature.com
Acanthamoeba spp. are facultative, opportunistic pathogens that are found in diverse
environments. In the hosts, they lead to multi-organ disease. Recent studies reported that …
environments. In the hosts, they lead to multi-organ disease. Recent studies reported that …
Elevated levels of PDGF-BB and VEGF are associated with a decreased risk of readmission or death in children with severe malarial anemia
MG Slaughter, S Bhumbra… - The Journal of …, 2024 - academic.oup.com
Background Children with severe malarial anemia (SMA) typically have low in-hospital
mortality but have a high risk of postdischarge readmission or death. We hypothesized that …
mortality but have a high risk of postdischarge readmission or death. We hypothesized that …
Cytoadhesion of Plasmodium falciparum‐Infected Red Blood Cells Changes the Expression of Cytokine‐, Histone‐ and Antiviral Protein‐Encoding Genes in Brain …
J Allweier, M Bartels, H Torabi… - Molecular …, 2024 - Wiley Online Library
Malaria remains a significant global health problem, mainly due to Plasmodium falciparum,
which is responsible for most fatal infections. Infected red blood cells (iRBCs) evade spleen …
which is responsible for most fatal infections. Infected red blood cells (iRBCs) evade spleen …
Gymnema inodorum leaf extract improves cardiac function in experimental mice infected with Plasmodium Berghei
S Ounjaijean, R Rattanatham… - Journal of Evidence …, 2023 - journals.sagepub.com
Malaria-associated cardiac injury has been reported to be the primary cause of death due to
severe malaria. The discovery of substances showing a protective effect on cardiac injury …
severe malaria. The discovery of substances showing a protective effect on cardiac injury …