The role of smoking in the mechanisms of development of chronic obstructive pulmonary disease and atherosclerosis
S Kotlyarov - International Journal of Molecular Sciences, 2023 - mdpi.com
Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD) and
atherosclerotic cardiovascular disease (ASCVD). These diseases share common …
atherosclerotic cardiovascular disease (ASCVD). These diseases share common …
[HTML][HTML] Inducible NOS inhibition reverses tobacco-smoke-induced emphysema and pulmonary hypertension in mice
M Seimetz, N Parajuli, A Pichl, F Veit, G Kwapiszewska… - Cell, 2011 - cell.com
Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death
worldwide. We report in an emphysema model of mice chronically exposed to tobacco …
worldwide. We report in an emphysema model of mice chronically exposed to tobacco …
Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease
H Yao, I Rahman - Toxicology and applied pharmacology, 2011 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a global health problem. The current
therapies for COPD are poorly effective and the mainstays of pharmacotherapy are …
therapies for COPD are poorly effective and the mainstays of pharmacotherapy are …
Group 3 pulmonary hypertension: from bench to bedside
N Singh, P Dorfmüller, OA Shlobin… - Circulation …, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3
PH in the most recent classification system. Prevalence of these diseases is increasing over …
PH in the most recent classification system. Prevalence of these diseases is increasing over …
The role of the endothelium in asthma and chronic obstructive pulmonary disease (COPD)
COPD and asthma are important chronic inflammatory disorders with a high associated
morbidity. Much research has concentrated on the role of inflammatory cells, such as the …
morbidity. Much research has concentrated on the role of inflammatory cells, such as the …
Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases
Significance: Chronic obstructive pulmonary disease (COPD) is predominantly a tobacco
smoke-triggered disease with features of chronic low-grade systemic inflammation and …
smoke-triggered disease with features of chronic low-grade systemic inflammation and …
Animal models of pulmonary hypertension: Getting to the heart of the problem
JP Dignam, TE Scott, BK Kemp‐Harper… - British Journal of …, 2022 - Wiley Online Library
Despite recent therapeutic advances, pulmonary hypertension (PH) remains a fatal disease
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …
due to the development of right ventricular (RV) failure. At present, no treatments targeted at …
Pulmonary hypertension in chronic obstructive pulmonary disease
Even mild pulmonary hypertension (PH) is associated with increased mortality and morbidity
in patients with chronic obstructive pulmonary disease (COPD). However, the underlying …
in patients with chronic obstructive pulmonary disease (COPD). However, the underlying …
Animal models and mechanisms of tobacco smoke-induced chronic obstructive pulmonary disease (COPD)
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, and its global health burden is increasing. COPD is characterized by …
worldwide, and its global health burden is increasing. COPD is characterized by …
Effects of cigarette smoke on pulmonary endothelial cells
Cigarette smoking is the leading cause of preventable disease and death in the United
States. Cardiovascular comorbidities associated with both active and secondhand cigarette …
States. Cardiovascular comorbidities associated with both active and secondhand cigarette …