Mechanisms of pathogenicity for the emerging fungus Candida auris

MV Horton, AM Holt, JE Nett - Plos Pathogens, 2023 - journals.plos.org
Candida auris recently emerged as an urgent public health threat, causing outbreaks of
invasive infections in healthcare settings throughout the world. This fungal pathogen persists …

The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen

DJ Santana, G Zhao, TR O'Meara - Plos Pathogens, 2024 - journals.plos.org
Candida auris is an emerging fungal pathogen with unusual evolutionary history—there are
multiple distinct phylogeographic clades showing a near simultaneous transition from a …

A Candida auris–specific adhesin, Scf1, governs surface association, colonization, and virulence

DJ Santana, JAE Anku, G Zhao, R Zarnowski… - Science, 2023 - science.org
Candida auris is an emerging fungal pathogen responsible for health care–associated
outbreaks that arise from persistent surface and skin colonization. We characterized the …

Therapeutic implications of C. albicans-S. aureus mixed biofilm in a murine subcutaneous catheter model of polymicrobial infection

T Vila, EF Kong, D Montelongo-Jauregui, P Van Dijck… - Virulence, 2021 - Taylor & Francis
Biofilm-associated polymicrobial infections tend to be challenging to treat. Candida albicans
and Staphylococcus aureus are leading pathogens due to their ability to form biofilms on …

Differential skin immune responses in mice intradermally infected with Candida auris and Candida albicans

A Datta, D Das, JE Nett, JM Vyas… - Microbiology …, 2023 - Am Soc Microbiol
Candida auris, an emerging multi-drug-resistant fungal pathogen, uniquely colonizes the
human skin long term, leading to subsequent development of life-threatening invasive …

Overview about Candida auris: what's up 12 years after its first description?

G Desoubeaux, AT Coste, C Imbert… - Journal of Medical …, 2022 - Elsevier
Candida auris has been described as an emerging yeast species during the last decade. As
many as 25% of its strains may naturally exhibit multi-drug resistance to the currently …

Beyond ergosterol: Strategies for combatting antifungal resistance in Aspergillus fumigatus and Candida auris

R Cruz, WM Wuest - Tetrahedron, 2023 - Elsevier
Aspergillus fumigatus and Candida auris are historically problematic fungal pathogens
responsible for systemic infections and high mortality rates, especially in …

Colonization by Candida auris in critically ill patients: role of cutaneous and rectal localization during an outbreak

G Piatti, M Sartini, C Cusato, AM Schito - Journal of Hospital Infection, 2022 - Elsevier
Background Candida auris infections have been reported worldwide since the pathogen
was isolated in 2009. Aim To analyse the incidence of cutaneous and intestinal colonization …

Intestinal colonization with Candida auris and mucosal immune response in mice treated with cefoperazone oral antibiotic

D Das, H HogenEsch, S Thangamani - Frontiers in Immunology, 2023 - frontiersin.org
Candida auris, an emerging multi-drug resistant fungal pathogen, causes invasive infections
in humans. The factors regulating the colonization of C. auris in host niches are not well …

Lansoprazole interferes with fungal respiration and acts synergistically with amphotericin B against multidrug-resistant Candida auris

EA Salama, Y Elgammal, A Wijeratne… - Emerging microbes & …, 2024 - Taylor & Francis
Candida auris has emerged as a problematic fungal pathogen associated with high
morbidity and mortality. Amphotericin B (AmB) is the most effective antifungal used to treat …