Fatty acid metabolism disorders and potential therapeutic traditional Chinese medicines in cardiovascular diseases

X Liu, X Xu, T Zhang, L Xu, H Tao, Y Liu… - Phytotherapy …, 2023 - Wiley Online Library
Cardiovascular diseases are currently the primary cause of mortality in the whole world.
Growing evidence indicated that the disturbances in cardiac fatty acid metabolism are …

[HTML][HTML] Mass spectrometry-based metabolomics for discovering active ingredients and exploring action mechanism of herbal medicine

S Guo, S Qiu, Y Cai, Z Wang, Q Yang, S Tang… - Frontiers in …, 2023 - frontiersin.org
Natural products derived from herbal medicine are a fruitful source of lead compounds
because of their structural diversity and potent bioactivities. However, despite the success of …

[HTML][HTML] The bile acid membrane receptor TGR5 in cancer: friend or foe?

Y Qi, G Duan, D Wei, C Zhao, Y Ma - Molecules, 2022 - mdpi.com
The G-protein-coupled bile acid receptor, Gpbar1 or TGR5, is characterized as a membrane
receptor specifically activated by bile acids. A series of evidence shows that TGR5 induces …

Effects of Xinkeshu tablets on coronary heart disease patients combined with anxiety and depression symptoms after percutaneous coronary intervention: A meta …

M Chen, M Liu, X Guo, J Zhou, H Yang, G Zhong… - Phytomedicine, 2022 - Elsevier
Background Xinkeshu tablets (XKS), a well-known Chinese patent drug, have been
administered to coronary heart disease (CHD) patients with anxiety and depression after …

PLGA nanoparticles enhanced cardio-protection of scutellarin and paeoniflorin against isoproterenol-induced myocardial ischemia in rats

C Yang, S Yang, S Fang, L Li, J Jing, W Liu… - International Journal of …, 2023 - Elsevier
This study aims to examine the impact of the microfluidic preparation process on the quality
of poly (lactic-co-glycolic acid)(PLGA) nanoparticles (NPs) co-delivered with scutellarin …

[HTML][HTML] Crosstalk among Reactive Oxygen Species, Autophagy and Metabolism in Myocardial Ischemia and Reperfusion Stages

Y Peng, Y Tao, L Liu, J Zhang, B Wei - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Myocardial ischemia is the most common cardiovascular disease. Reperfusion, an important
myocardial ischemia tool, causes unexpected and irreversible damage to cardiomyocytes …

Microbiome-metabolome reveals that the Suxiao Jiuxin pill attenuates acute myocardial infarction associated with fatty acid metabolism

J Liao, Y Zhang, C Ma, G Wu, W Zhang - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance The Suxiao Jiuxin pill (SJP) is a Chinese medical
patent drug on the national essential drug list of China, with well-established cardiovascular …

[HTML][HTML] Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice

ZY Wu, L Luo, YQ Kan, ML Qin, HT Li, QZ He, HC Zeng - Toxics, 2023 - mdpi.com
Bisphenol S (BPS) is an environmental pollutant that can accumulate in the human body
and cause harm. Puerarin (PUE) is a flavonoid with anti-inflammatory and antioxidant …

Analysis of inter-individual variability of antitussive effect of Farfarae Flos and its fecal metabolites based on gut microbiota

L Yang, S Yu, X Qin, Z Li - Journal of Pharmaceutical and Biomedical …, 2022 - Elsevier
In this study, the inter-individual variability of antitussive effect of Farfarae Flos was
observed, and then the Farfarae Flos treated mice were divided into the mice with good or …

[HTML][HTML] Metabolomics analysis reveals the effects of Salvia Miltiorrhiza Bunge extract on ameliorating acute myocardial ischemia in rats induced by isoproterenol

X Mu, H Yu, H Li, L Feng, N Ta, L Ling, L Bai, A Rure… - Heliyon, 2024 - cell.com
Salvia miltiorrhiza Bunge (SM) is a widespread herbal therapy for myocardial ischemia (MI).
Nevertheless, the therapeutic signaling networks of SM extract on MI is yet unknown …