Medical applications of synchrotron radiation

P Suortti, W Thomlinson - Physics in Medicine & Biology, 2003 - iopscience.iop.org
The medical imaging and therapeutic technologies that are based on the use of radiation
are reviewed briefly, with special emphasis on the recent developments of synchrotron …

Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue

E Bräuer-Krisch, R Serduc, EA Siegbahn… - … Research/Reviews in …, 2010 - Elsevier
Microbeam radiation therapy (MRT) uses highly collimated, quasi-parallel arrays of X-ray
microbeams of 50–600keV, produced by third generation synchrotron sources, such as the …

Response of rat intracranial 9L gliosarcoma to microbeam radiation therapy

FA Dilmanian, TM Button, G Le Duc, N Zhong… - Neuro …, 2002 - academic.oup.com
Radiotherapeutic doses for malignant gliomas are generally palliative because greater,
supposedly curative doses would impart clinically unacceptable damage to nearby vital …

Interlaced x-ray microplanar beams: a radiosurgery approach with clinical potential

FA Dilmanian, Z Zhong, T Bacarian… - Proceedings of the …, 2006 - National Acad Sciences
Studies have shown that x-rays delivered as arrays of parallel microplanar beams
(microbeams), 25-to 90-μm thick and spaced 100–300 μm on-center, respectively, spare …

[HTML][HTML] Microbeam radiation therapy: Clinical perspectives

MA Grotzer, E Schültke, E Bräuer-Krisch, JA Laissue - Physica Medica, 2015 - Elsevier
Microbeam radiation therapy (MRT), a novel form of spatially fractionated radiotherapy (RT),
uses arrays of synchrotron-generated X-ray microbeams (MB). MRT has been identified as a …

FLASH and minibeams in radiation therapy: the effect of microstructures on time and space and their potential application to protontherapy

A Mazal, Y Prezado, C Ares, L de Marzi… - The British Journal of …, 2020 - academic.oup.com
After years of lethargy, studies on two non-conventional microstructures in time and space of
the beams used in radiation therapy are enjoying a huge revival. The first effect called …

Radiochromic film dosimetry

CG Soares - Radiation measurements, 2006 - Elsevier
The object of this paper is to give a new user some practical information on the use of
radiochromic films for medical applications. While various aspects of radiochromic film …

Weanling piglet cerebellum: a surrogate for tolerance to MRT (microbeam radiation therapy) in pediatric neuro-oncology

JA Laissue, H Blattmann, M Di Michiel… - … and Applications III, 2001 - spiedigitallibrary.org
The cerebellum of the weanling piglet (Yorkshire) was used as a surrogate for the
radiosensitive human infant cerebellum in a Swiss-led program of experimental microbeam …

In vivo two-photon microscopy study of short-term effects of microbeam irradiation on normal mouse brain microvasculature

R Serduc, P Vérant, JC Vial, R Farion, L Rocas… - International Journal of …, 2006 - Elsevier
Purpose: The purpose of this study was to assess the early effects of microbeam irradiation
on the vascular permeability and volume in the parietal cortex of normal nude mice using …

[HTML][HTML] Effects of microbeam radiation therapy on normal and tumoral blood vessels

A Bouchet, R Serduc, JA Laissue, V Djonov - Physica Medica, 2015 - Elsevier
Microbeam radiation therapy (MRT) is a new form of preclinical radiotherapy using quasi-
parallel arrays of synchrotron X-ray microbeams. While the deposition of several hundred …