Drug repurposing approaches towards defeating multidrug-resistant gram-negative pathogens: Novel polymyxin/non-antibiotic combinations
Multidrug-resistant (MDR) Gram-negative pathogens remain an unmet public health threat.
In recent times, increased rates of resistance have been reported not only to commonly used …
In recent times, increased rates of resistance have been reported not only to commonly used …
In silico and in vitro studies of GENT-EDTA encapsulated niosomes: A novel approach to enhance the antibacterial activity and biofilm inhibition in drug-resistant …
I Akbarzadeh, N Rezaei, S Bazzazan, MN Mezajin… - Biomaterials …, 2023 - Elsevier
Klebsiella pneumoniae (Kp) is a common pathogen inducing catheter-related biofilm
infections. Developing effective therapy to overcome antimicrobial resistance (AMR) in Kp is …
infections. Developing effective therapy to overcome antimicrobial resistance (AMR) in Kp is …
Ciprofloxacin- and levofloxacin-loaded nanoparticles efficiently suppressed fluoroquinolone resistance and biofilm formation in Acinetobacter baumannii
The spread of fluoroquinolone (FQ) resistance in Acinetobacter baumannii represents a
critical health threat. This study aims to overcome FQ resistance in A. baumannii via the …
critical health threat. This study aims to overcome FQ resistance in A. baumannii via the …
Polyethylene glycol enhanced antibacterial activity of EDTA and ethyl maltol blended PLA against Staphylococcus aureus for biodegradable active packaging
A Srisa, N Harnkarnsujarit - Food Bioscience, 2024 - Elsevier
Abstract Poly (lactic acid)(PLA) has limited promise as a bio-based antimicrobial packaging
material due to its lack of plasticization, which limits antimicrobial agent release and …
material due to its lack of plasticization, which limits antimicrobial agent release and …
The effect of combinations of a glyphosate-based herbicide with various clinically used antibiotics on phenotypic traits of Gram-negative species from the ESKAPEE …
H Zerrouki, A Hamieh, L Hadjadj, JM Rolain… - Scientific Reports, 2024 - nature.com
The emission of glyphosate and antibiotic residues from human activities threatens the
diversity and functioning of the microbial community. This study examines the impact of a …
diversity and functioning of the microbial community. This study examines the impact of a …
Efficacy of outer membrane permeabilization in promoting aromatic isothiocyanates-mediated eradication of multidrug resistant Gram-negative bacteria and bacterial …
CC Lo, TH Yeh, YH Jao, TH Wang, HR Lo - Folia Microbiologica, 2024 - Springer
Multidrug resistant (MDR) bacteria are recognized to be one of the most important problems
in public health. The outer membrane permeability is a critical intrinsic mechanism of …
in public health. The outer membrane permeability is a critical intrinsic mechanism of …
Proteomic signatures of synergistic interactions in antimicrobials
Mounting evidence has shown that antimicrobial agents can interfere synergistically with
bacterial viability and proliferation when acting together at both the planktonic and biofilm …
bacterial viability and proliferation when acting together at both the planktonic and biofilm …
Inhibition of Candida albicans and Staphylococcus epidermidis mixed biofilm formation in a catheter disk model system treated with EtOH–EDTA solution
MFG Lagudas, KJC Bureros - Letters in Applied Microbiology, 2023 - academic.oup.com
Microbial colonization and the formation of biofilms on catheter surfaces pose a great risk for
medical-related infections. We aimed (a) to evaluate polymicrobial biofilm formation of …
medical-related infections. We aimed (a) to evaluate polymicrobial biofilm formation of …
Adjunctive intravesical EDTA-tromethamine treatment of a biofilm-associated recurrent Escherichia coli cystitis in a dog
V Leynaud, NP Jousserand, MN Lucas… - The Canadian …, 2024 - ingentaconnect.com
A 15-month-old spayed female greater Swiss mountain dog was brought to our clinic
because of relapsing episodes of urinary tract infection, present since her adoption at 2 mo …
because of relapsing episodes of urinary tract infection, present since her adoption at 2 mo …
Development of Antibiotic-Encapsulated Escherichia coli Outer Membrane Vesicles as Novel Antibiotic Agent to Overcome Resistance Mechanism
M Wu - 2024 - search.proquest.com
Abstract Development of novel antimicrobial agents against Gram-negative bacteria is
hindered by the intrinsic and acquired resistance mechanisms, such as the presence of dual …
hindered by the intrinsic and acquired resistance mechanisms, such as the presence of dual …