Hepatorenal syndrome: pathophysiology, diagnosis, and management

DA Simonetto, P Gines, PS Kamath - bmj, 2020 - bmj.com
Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

News in pathophysiology, definition and classification of hepatorenal syndrome: a step beyond the International Club of Ascites (ICA) consensus document

P Angeli, G Garcia-Tsao, MK Nadim, CR Parikh - Journal of hepatology, 2019 - Elsevier
Renal dysfunction is a common, life-threatening complication occurring in patients with liver
disease. Hepatorenal syndrome (HRS) has been defined as a purely “functional” type of …

Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: 2021 practice guidance by the American Association …

SW Biggins, P Angeli, G Garcia‐Tsao, P Ginès… - …, 2021 - Wiley Online Library
This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

P Angeli, M Bernardi, C Villanueva, C Francoz… - Journal of …, 2018 - Elsevier
The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites

P Angeli, P Ginès, F Wong, M Bernardi, TD Boyer… - Gut, 2015 - gut.bmj.com
Acute renal failure (ARF) is a common complication in patients with decompensated
cirrhosis. The traditional diagnostic criteria of renal failure in these patients were proposed in …

Biomarkers of acute and chronic kidney disease

WR Zhang, CR Parikh - Annual review of physiology, 2019 - annualreviews.org
The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

Management of the critically ill patient with cirrhosis: a multidisciplinary perspective

MK Nadim, F Durand, JA Kellum, J Levitsky… - Journal of …, 2016 - Elsevier
Methods Prior to the conference, the organizing committee identified topics relevant to the
management of patients with ACLF. A diverse international panel representing multiple …

[PDF][PDF] Management of adult patients with ascites due to cirrhosis: an update

BA Runyon - Hepatology, 2009 - Wiley Online Library
A Medline search from 1966 through 2007 was performed; search terms included ascites,
hepatorenal syndrome, diet therapy, drug therapy, radiotherapy, surgery, and therapy. The …

[PDF][PDF] Kidney biomarkers and differential diagnosis of patients with cirrhosis and acute kidney injury

JM Belcher, AJ Sanyal, AJ Peixoto, MA Perazella… - …, 2014 - Wiley Online Library
Acute kidney injury (AKI) is common in patients with cirrhosis and associated with significant
mortality. The most common etiologies of AKI in this setting are prerenal azotemia (PRA) …

[PDF][PDF] Neutrophil gelatinase‐associated lipocalin for assessment of acute kidney injury in cirrhosis: a prospective study

P Huelin, E Solà, C Elia, C Solé, A Risso… - …, 2019 - Wiley Online Library
Kidney biomarkers appear to be useful in differential diagnosis between acute tubular
necrosis (ATN) and other types of acute kidney injury (AKI) in cirrhosis, particularly …