Gold nanoparticles in neurological diseases: A review of neuroprotection

MC Chiang, YP Yang, CJB Nicol, CJ Wang - International Journal of …, 2024 - mdpi.com
This review explores the diverse applications of gold nanoparticles (AuNPs) in neurological
diseases, with a specific focus on Alzheimer's disease (AD), Parkinson's disease (PD), and …

Novel Multi-antioxidant Approach for ischemic stroke therapy targeting the role of oxidative stress

C Briones-Valdivieso, F Briones, S Orellana-Urzúa… - Biomedicines, 2024 - mdpi.com
Stroke is a major contributor to global mortality and disability. While reperfusion is essential
for preventing neuronal death in the penumbra, it also triggers cerebral ischemia …

Reactive Oxygen Species-Responsive Chitosan–Bilirubin Nanoparticles Loaded with Statin for Treatment of Cerebral Ischemia

R Nagareddy, JH Kim, JH Kim, RG Thomas… - Biomaterials …, 2024 - spj.science.org
Cerebral ischemia impairs blood circulation, leading to elevated reactive oxygen species
(ROS) production. A ROS-responsive delivery of drugs can enhance the therapeutic efficacy …

Res@ LDH: A Novel Nanohybrid Therapeutic for Ischemia–Reperfusion Injury with Dual Reactive Oxygen Species Scavenging Efficiency

M Liu, S Liu, Y Bai, M Zhang, D Zhang, R Sun… - Biomaterials …, 2024 - spj.science.org
Ischemic stroke poses a global health challenge, necessitating effective therapeutic
interventions given the limited time window for thrombolytic therapy. Here, we present Res …

Advancing stroke therapy: the potential of MOF-based nanozymes in biomedical applications

M Chen, Y Qin, Y Peng, R Mai, H Teng… - … in Bioengineering and …, 2024 - frontiersin.org
In this study, we explored the growing use of metal-organic framework (MOF)-based
Nanozymes in biomedical research, with a specific emphasis on their applications in stroke …

Advanced Nano-Drug Delivery Systems in the Treatment of Ischemic Stroke

J Zhang, Z Chen, Q Chen - Molecules, 2024 - mdpi.com
In recent years, the frequency of strokes has been on the rise year by year and has become
the second leading cause of death around the world, which is characterized by a high …

Cerium oxide nanoparticles (nanoceria) pretreatment attenuates cell death in the hippocampus and cognitive dysfunction due to repeated isoflurane anesthesia in …

E Kargı-Gemici, A Şengelen, Y Aksüt, O Akyol… - NeuroToxicology, 2024 - Elsevier
General anesthetics exposure, particularly prolonged or repeated exposure, is a crucial
cause of neurological injuries. Notably, isoflurane (ISO), used in pediatric anesthesia …

Emerging Promise of Green Synthesized Metallic Nanoparticles for the Management of Neurological Disorders

ZE Moghadam, S Hamidi, M Azarfarin… - Current …, 2024 - benthamdirect.com
The management of neurological disorders is very challenging due to the presence of the
blood-brain barrier (BBB) that prevents the entry of drugs into the central nervous system …

One‐Pot Synthesis and Characterization of Magnetic α‐Fe2O3/CuO/CuFe2O4 Nanocomposite for Multifunctional Therapeutic Applications

FA Sahara, MS Sultana, MK Amin… - …, 2024 - Wiley Online Library
This study demonstrates a novel nanostructured drug delivery system utilizing α‐
Fe2O3/CuO/CuFe2O4 ternary nanocomposite for effective drug transport in sick tissues …

[PDF][PDF] Utilizing reactive oxygen species-scavenging nanoparticles for targeting oxidative stress in the treatment of ischemic stroke: A review

L Shao, C Wang, G Xu, Z Tu, X Yu, C Weng, J Liu… - Open …, 2024 - degruyter.com
Ischemic stroke, which accounts for the majority of stroke cases, triggers a complex series of
pathophysiological events, prominently characterized by acute oxidative stress due to …