Multiple endocrine neoplasia type 1 and Zollinger-Ellison syndrome: a prospective study of 107 cases and comparison with 1009 cases from the literature

F Gibril, M Schumann, A Pace, RT Jensen - Medicine, 2004 - journals.lww.com
In patients with multiple endocrine neoplasia type 1 (MEN1), the most common functional
pancreatic endocrine tumor (PET) syndrome is Zollinger-Ellison syndrome (ZES). ZES has …

[HTML][HTML] Gastrinoma

RT Jensen, T Ito - Endotext [Internet], 2023 - ncbi.nlm.nih.gov
Gastrinomas are neuroendocrine neoplasms (NENs), that occur primarily in the duodenum
and pancreas, which ectopically secrete gastrin, resulting in the Zollinger-Ellison syndrome …

ENETS consensus guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes

RT Jensen, G Cadiot, ML Brandi, WW De Herder… - …, 2012 - karger.com
Gastrinomas are neuroendocrine neoplasms, usually located in the duodenum or pancreas,
that secrete gastrin and cause a clinical syndrome known as Zollinger-Ellison syndrome …

Islet cell tumors of the pancreas: pathologic-imaging correlation among size, necrosis and cysts, calcification, malignant behavior, and functional status.

PC Buetow, TV Parrino, JL Buck… - … American journal of …, 1995 - Am Roentgen Ray Soc
The purpose of our study was to correlate the imaging and pathologic features of islet cell
tumors with regard to tumor size, necrosis and cysts, calcification, malignant behavior, and …

Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex.

MS German, J Wang, RB Chadwick… - Genes & …, 1992 - genesdev.cshlp.org
The distal portion of the rat insulin I gene 5'-flanking DNA contains two sequence elements,
the Far and FLAT elements, that can function in combination, but not separately, as a beta …

VIP: molecular biology and neurobiological function

I Gozes, DE Brenneman - Molecular neurobiology, 1989 - Springer
In the mammalian brain, a major regulatory peptide is vasoactive intestinal peptide (VIP).
This 28 amino acid peptide, originally isolated from the porcine duodenum, was later found …

[PDF][PDF] Elemental composition of secretory granules in pancreatic islets of Langerhans

MC Foster, RD Leapman, MX Li, I Atwater - Biophysical journal, 1993 - cell.com
We have characterized, by electron probe microanalysis, rapidly frozen cultured rat islets at
the level of individual secretory granules. Elemental analysis of thin, dried cryosections …

Resection of pancreatic neuroendocrine tumors: results of 70 cases

KK Kazanjian, HA Reber, OJ Hines - Archives of surgery, 2006 - jamanetwork.com
Hypothesis Neuroendocrine tumors of the pancreas can be managed surgically with
excellent outcomes. Design Retrospective case series. Setting Academic medical center …

Islet cell tumors of the pancreas: clinical, radiologic, and pathologic correlation in diagnosis and localization.

PC Buetow, DL Miller, TV Parrino, JL Buck - Radiographics, 1997 - pubs.rsna.org
Islet cell tumors are rare pancreatic or peripancreatic neoplasms that produce and secrete
hormones to a variable degree. These tumors are best divided on clinical grounds into those …

Insulinomas associated with multiple endocrine neoplasia type I: the need for a different surgical approach

MJ Demeure, DC Klonoff, JH Karam, QY Duh, OH Clark - Surgery, 1991 - surgjournal.com
Abstract Insulinomas are usually solitary (> 90%) benign pancreatic tumors readily cured by
enucleation or resection. To determine whether the 4% of insulinomas associated with …