Brown adipose tissue—a translational perspective

AC Carpentier, DP Blondin, F Haman… - Endocrine …, 2023 - academic.oup.com
Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

[HTML][HTML] What we talk about when we talk about fat

ED Rosen, BM Spiegelman - Cell, 2014 - cell.com
There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Craniopharyngioma

HL Müller, C Alapetite, J Wisoff - Brain and Spinal Tumors of …, 2020 - taylorfrancis.com
Craniopharyngiomas are rare, partly cystic and calcified embryonic malformations of the
sellar/parasellar region with low histological grade (WHO Io). A bimodal age distribution has …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

The vagus nerve and the inflammatory reflex—linking immunity and metabolism

VA Pavlov, KJ Tracey - Nature Reviews Endocrinology, 2012 - nature.com
The vagus nerve has an important role in regulation of metabolic homeostasis, and efferent
vagus nerve-mediated cholinergic signalling controls immune function and proinflammatory …

Leptin and brain–adipose crosstalks

A Caron, S Lee, JK Elmquist, L Gautron - Nature Reviews …, 2018 - nature.com
Interactions between the brain and distinct adipose depots have a key role in maintaining
energy balance, thereby promoting survival in response to metabolic challenges such as …

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

MN Harvie, M Pegington, MP Mattson… - International journal of …, 2011 - nature.com
Background: The problems of adherence to energy restriction in humans are well known.
Objective: To compare the feasibility and effectiveness of intermittent continuous energy …

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

C Dibner, U Schibler, U Albrecht - Annual review of physiology, 2010 - annualreviews.org
Most physiology and behavior of mammalian organisms follow daily oscillations. These
rhythmic processes are governed by environmental cues (eg, fluctuations in light intensity …

[HTML][HTML] The role of the autonomic nervous system in the pathophysiology of obesity

D Guarino, M Nannipieri, G Iervasi, S Taddei… - Frontiers in …, 2017 - frontiersin.org
Obesity is reaching epidemic proportions globally and represents a major cause of
comorbidities, mostly related to cardiovascular disease. The autonomic nervous system …

Role of microbiota-derived lipopolysaccharide in adipose tissue inflammation, adipocyte size and pyroptosis during obesity

LG Hersoug, P Møller, S Loft - Nutrition research reviews, 2018 - cambridge.org
It has been established that ingestion of a high-fat diet increases the blood levels of
lipopolysaccharides (LPS) from Gram-negative bacteria in the gut. Obesity is characterised …