Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

The developmental origins of health and disease hypothesis applied to neurodevelopmental
outcomes asserts that the fetal origins of future development are relevant to mental health …

Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Prenatal exposure to maternal stress, anxiety, and depression can have lasting effects on
infant development with risk of psychopathology. Although the impact of prenatal maternal …

Prenatal stress (PS) has been linked to abnormal cognitive, behavioral and psychosocial
outcomes in both animals and humans. Animal studies have clearly demonstrated PS effects …

BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …

Autistic-spectrum conditions and psychotic-spectrum conditions (mainly schizophrenia,
bipolar disorder, and major depression) represent two major suites of disorders of human …

Background. There has been a rise in the prevalence of large newborns over a few decades
in many parts of the world. There is ample evidence that fetal macrosomia is associated with …

Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

Size at birth is critical in determining life expectancy and is dependent primarily on the
placental supply of nutrients. However, the fetus is not just a passive recipient of nutrients …