Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives
Microfluidic chip technology is an emerging tool in the field of biomedical application.
Microfluidic chip includes a set of groves or microchannels that are engraved on different …
Microfluidic chip includes a set of groves or microchannels that are engraved on different …
Systems integration for global sustainability
BACKGROUND Many key global sustainability challenges are closely intertwined
(examples are provided in the figure). These challenges include air pollution, biodiversity …
(examples are provided in the figure). These challenges include air pollution, biodiversity …
Rotational manipulation of single cells and organisms using acoustic waves
The precise rotational manipulation of single cells or organisms is invaluable to many
applications in biology, chemistry, physics and medicine. In this article, we describe an …
applications in biology, chemistry, physics and medicine. In this article, we describe an …
On-chip manipulation of single microparticles, cells, and organisms using surface acoustic waves
Techniques that can dexterously manipulate single particles, cells, and organisms are
invaluable for many applications in biology, chemistry, engineering, and physics. Here, we …
invaluable for many applications in biology, chemistry, engineering, and physics. Here, we …
Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology
The nematode Caenorhabditis elegans has emerged as an important animal model in
various fields including neurobiology, developmental biology, and genetics. Characteristics …
various fields including neurobiology, developmental biology, and genetics. Characteristics …
Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery
Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …
powerful platforms for precise production of novel functional materials (eg, emulsion …
Functional regeneration after laser axotomy
Understanding how nerves regenerate is an important step towards developing treatments
for human neurological disease, but investigation has so far been limited to complex …
for human neurological disease, but investigation has so far been limited to complex …
High‐throughput screening and small animal models, where are we?
J Giacomotto, L Ségalat - British journal of pharmacology, 2010 - Wiley Online Library
Current high‐throughput screening methods for drug discovery rely on the existence of
targets. Moreover, most of the hits generated during screenings turn out to be invalid after …
targets. Moreover, most of the hits generated during screenings turn out to be invalid after …
High-throughput in vivo vertebrate screening
We demonstrate a high-throughput platform for cellular-resolution in vivo chemical and
genetic screens on zebrafish larvae. The system automatically loads zebrafish from …
genetic screens on zebrafish larvae. The system automatically loads zebrafish from …
Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans
Microscopy, phenotyping and visual screens are frequently applied to model organisms in
combination with genetics. Although widely used, these techniques for multicellular …
combination with genetics. Although widely used, these techniques for multicellular …