Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives

P Pattanayak, SK Singh, M Gulati, S Vishwas… - Microfluidics and …, 2021 - Springer
Microfluidic chip technology is an emerging tool in the field of biomedical application.
Microfluidic chip includes a set of groves or microchannels that are engraved on different …

Systems integration for global sustainability

J Liu, H Mooney, V Hull, SJ Davis, J Gaskell, T Hertel… - Science, 2015 - science.org
BACKGROUND Many key global sustainability challenges are closely intertwined
(examples are provided in the figure). These challenges include air pollution, biodiversity …

Rotational manipulation of single cells and organisms using acoustic waves

D Ahmed, A Ozcelik, N Bojanala, N Nama… - Nature …, 2016 - nature.com
The precise rotational manipulation of single cells or organisms is invaluable to many
applications in biology, chemistry, physics and medicine. In this article, we describe an …

On-chip manipulation of single microparticles, cells, and organisms using surface acoustic waves

X Ding, SCS Lin, B Kiraly, H Yue, S Li… - Proceedings of the …, 2012 - National Acad Sciences
Techniques that can dexterously manipulate single particles, cells, and organisms are
invaluable for many applications in biology, chemistry, engineering, and physics. Here, we …

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

MCK Leung, PL Williams, A Benedetto… - Toxicological …, 2008 - academic.oup.com
The nematode Caenorhabditis elegans has emerged as an important animal model in
various fields including neurobiology, developmental biology, and genetics. Characteristics …

Industrial lab-on-a-chip: Design, applications and scale-up for drug discovery and delivery

GT Vladisavljević, N Khalid, MA Neves… - Advanced drug delivery …, 2013 - Elsevier
Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …

Functional regeneration after laser axotomy

MF Yanik, H Cinar, HN Cinar, AD Chisholm, Y Jin… - Nature, 2004 - nature.com
Understanding how nerves regenerate is an important step towards developing treatments
for human neurological disease, but investigation has so far been limited to complex …

High‐throughput screening and small animal models, where are we?

J Giacomotto, L Ségalat - British journal of pharmacology, 2010 - Wiley Online Library
Current high‐throughput screening methods for drug discovery rely on the existence of
targets. Moreover, most of the hits generated during screenings turn out to be invalid after …

High-throughput in vivo vertebrate screening

C Pardo-Martin, TY Chang, BK Koo, CL Gilleland… - Nature …, 2010 - nature.com
We demonstrate a high-throughput platform for cellular-resolution in vivo chemical and
genetic screens on zebrafish larvae. The system automatically loads zebrafish from …

Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans

K Chung, MM Crane, H Lu - Nature methods, 2008 - nature.com
Microscopy, phenotyping and visual screens are frequently applied to model organisms in
combination with genetics. Although widely used, these techniques for multicellular …