Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been
the most widely used excipients for the stabilization of protein therapeutics for years. In …

Ionic liquids (ILs) exhibit potential as excipients to stabilize proteins in solutions. This mini-
review is not a detailed reference book on ILs, rather a brief overview of the main …

The present study utilizes molecular dynamics simulations to examine how different anions
compete for protein solvation in aqueous solutions of ionic liquids (ILs). Ubiquitin is used as …

This article describes the molecular mechanism by which tetraalkylammonium chloride ([R 4
N] Cl: R-= methyl (Me), ethyl (Et), propyl (Pr), butyl (Bu)) modulates the stability, folding, and …

This manuscript determines the factors by which the water-miscible ionic liquid (IL), 1-alkyl-3-
methylimidazolium chloride [Rmim] Cl affects the thermodynamic stability and CO …

The stability of two small proteins, one composed of three α-helices (α-peptide) and another
composed of a β-sheet (β-peptide) solvated in five different ionic liquids (ILs), is analyzed …

The chemical synthesis of a highly hydrophobic membrane-associated peptide by native
chemical ligation (NCL) in an ionic liquid (IL)[C2mim][OAc]/buffer mixture was achieved by …

allyl-3-methylimidazolium chloride (AMIMCl) acts as a potential green solvent for proteins.
The present work provides a possible pathway by which the structural, kinetic …

Abstract Analysis of kinetic and thermodynamic parameters measured for CO-association
reaction of Ferrocytochrome c (Ferrocyt c) under variable concentrations of 1-butyl-3 …

The novel green solvent, ionic liquids emerged as potential solvents in executing the various
in-vitro protein based applications. In the present study, we investigated the role of 1-allyl-3 …