The health effects of vitamin D supplementation: evidence from human studies

R Bouillon, D Manousaki, C Rosen… - Nature Reviews …, 2022 - nature.com
Vitamin D supplementation can prevent and cure nutritional rickets in infants and children.
Preclinical and observational data suggest that the vitamin D endocrine system has a wide …

Vitamin D and risk for type 2 diabetes in people with prediabetes: a systematic review and meta-analysis of individual participant data from 3 randomized clinical trials

AG Pittas, T Kawahara, R Jorde… - Annals of internal …, 2023 - acpjournals.org
Background: The role of vitamin D in people who are at risk for type 2 diabetes remains
unclear. Purpose: To evaluate whether administration of vitamin D decreases risk for …

An update on vitamin D metabolism

F Saponaro, A Saba, R Zucchi - International journal of molecular …, 2020 - mdpi.com
Vitamin D is a steroid hormone classically involved in the calcium metabolism and bone
homeostasis. Recently, new and interesting aspects of vitamin D metabolism has been …

Vitamin D and obesity: current evidence and controversies

I Karampela, A Sakelliou, N Vallianou… - Current obesity …, 2021 - Springer
Abstract Purpose of Review Evidence from observational studies suggests that obesity is
associated with low vitamin D. As both obesity and hypovitaminosis D present an alarmingly …

Consensus statement on Vitamin D status assessment and supplementation: whys, whens, and hows

A Giustina, JP Bilezikian, RA Adler, G Banfi… - Endocrine …, 2024 - academic.oup.com
Abstract The 6th International Conference,“Controversies in Vitamin D,” was convened to
discuss controversial topics, such as vitamin D metabolism, assessment, actions, and …

Effects of vitamin D supplementation on prevention of type 2 diabetes in patients with prediabetes: a systematic review and meta-analysis

Y Zhang, H Tan, J Tang, J Li, W Chong, Y Hai… - Diabetes …, 2020 - Am Diabetes Assoc
BACKGROUND While observational studies have shown an association between vitamin D
insufficiency and diabetes, it is unclear whether intervention with vitamin D supplements can …

[HTML][HTML] Vitamin D: production, metabolism and mechanisms of action

DD Bikle - 2015 - europepmc.org
Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels
of sunlight exposure that do not burn the skin. Further metabolism of vitamin D to its major …

Association of body weight with response to vitamin D supplementation and metabolism

DK Tobias, H Luttmann-Gibson, S Mora… - JAMA Network …, 2023 - jamanetwork.com
Importance In the Vitamin D and Omega-3 Trial (VITAL), the effects of randomized vitamin D
supplementation (cholecalciferol), 2000 IU/d, reduced the risk of several health outcomes …

Vitamin D and obesity/adiposity—a brief overview of recent studies

I Bennour, N Haroun, F Sicard, L Mounien, JF Landrier - Nutrients, 2022 - mdpi.com
Observational studies classically find an inverse relationship between human plasma 25-
hydroxyvitamin D concentration and obesity. However, interventional and genetic studies …

Vitamin D: Newer concepts of its metabolism and function at the basic and clinical level

DD Bikle - Journal of the Endocrine Society, 2020 - academic.oup.com
The interest in vitamin D continues unabated with thousands of publications contributing to a
vast and growing literature each year. It is widely recognized that the vitamin D receptor …