Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …
A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
Abstract The COVID-19-, SARS-and MERS-related coronaviruses share many genomic and
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …
structural similarities. However, the SARS-CoV-2 is less pathogenic than SARS-CoV and …
[HTML][HTML] The role of SARS-CoV-2 accessory proteins in immune evasion
Many questions on the SARS-CoV-2 pathogenesis remain to answer. The SARS-CoV-2
genome encodes some accessory proteins that are essential for infection. Notably …
genome encodes some accessory proteins that are essential for infection. Notably …
Coronavirus disease (COVID-19): Current status and prospects for drug and vaccine development
K Ita - Archives of medical research, 2021 - Elsevier
The Coronavirus disease 2019 (COVID-19) pandemic has spread to almost all nooks and
corners of the world. There are numerous potential approaches to pharmacologically fight …
corners of the world. There are numerous potential approaches to pharmacologically fight …
[HTML][HTML] Role of machine learning techniques to tackle the COVID-19 crisis: systematic review
Background: SARS-CoV-2, the novel coronavirus responsible for COVID-19, has caused
havoc worldwide, with patients presenting a spectrum of complications that have pushed …
havoc worldwide, with patients presenting a spectrum of complications that have pushed …
Utilizing drug repurposing against COVID-19–efficacy, limitations, and challenges
V Parvathaneni, V Gupta - Life sciences, 2020 - Elsevier
The recent outbreak of Coronavirus disease (COVID-19), first in Eastern Asia and then
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
essentially across the world has been declared a pandemic by the WHO. COVID-19 is …
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
There is an urgent need for antivirals to treat the newly emerged severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). To identify new candidates, we screen a …
syndrome coronavirus 2 (SARS-CoV-2). To identify new candidates, we screen a …
The role of macrophages in the pathogenesis of SARS-CoV-2-associated acute respiratory distress syndrome
A Kosyreva, D Dzhalilova, A Lokhonina… - Frontiers in …, 2021 - frontiersin.org
Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …
A systematic review of the global intervention for SARS-CoV-2 combating: from drugs repurposing to molnupiravir approval
NA Ashour, A Abo Elmaaty, AA Sarhan… - Drug design …, 2023 - Taylor & Francis
The rising outbreak of SARS-CoV-2 continues to unfold all over the world. The development
of novel effective antiviral drugs to fight against SARS-CoV-2 is a time cost. As a result, some …
of novel effective antiviral drugs to fight against SARS-CoV-2 is a time cost. As a result, some …
Role of comorbidities like diabetes on severe acute respiratory syndrome coronavirus-2: A review
Pandemic coronavirus disease-2019, commonly known as COVID-19 caused by severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious disease …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly contagious disease …
Identification of Small Molecule Inhibitors of the Deubiquitinating Activity of the SARS-CoV-2 Papain-Like Protease: in silico Molecular Docking Studies and in vitro …
COVID-19 is an ongoing pandemic caused by the SARS-CoV-2 virus with important political,
socio-economic, and public health consequences. Inhibiting replication represents an …
socio-economic, and public health consequences. Inhibiting replication represents an …