Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

[HTML][HTML] Curcumin: biological, pharmaceutical, nutraceutical, and analytical aspects

RR Kotha, DL Luthria - Molecules, 2019 - mdpi.com
Turmeric is a curry spice that originated from India, which has attracted great interest in
recent decades because it contains bioactive curcuminoids (curcumin, demethoxycurcumin …

[HTML][HTML] Healthy effects of plant polyphenols: molecular mechanisms

M Leri, M Scuto, ML Ontario, V Calabrese… - International journal of …, 2020 - mdpi.com
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …

[HTML][HTML] Neuroprotective activities of curcumin in Parkinson's disease: a review of the literature

EE Nebrisi - International journal of molecular sciences, 2021 - mdpi.com
Parkinson's disease (PD) is a slowly progressive multisystem disorder affecting
dopaminergic neurons of the substantia nigra pars compacta (SNpc), which is characterized …

Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders

H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …

Protective effects of Indian spice curcumin against amyloid-β in Alzheimer's disease

PH Reddy, M Manczak, X Yin… - Journal of …, 2018 - content.iospress.com
The purpose of our article is to assess the current understanding of Indian spice, curcumin,
against amyloid-ß (Aß)-induced toxicity in Alzheimer's disease (AD) pathogenesis. Natural …

Curcumin, a component of golden spice: from bedside to bench and back

S Prasad, SC Gupta, AK Tyagi, BB Aggarwal - Biotechnology advances, 2014 - Elsevier
Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of
years, it is only within the past century that we learned about the chemistry of its active …

[HTML][HTML] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

S Prasad, AK Tyagi… - Cancer research and …, 2014 - synapse.koreamed.org
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral …

Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

O Naksuriya, S Okonogi, RM Schiffelers, WE Hennink - Biomaterials, 2014 - Elsevier
Curcumin, a natural yellow phenolic compound, is present in many kinds of herbs,
particularly in Curcuma longa Linn.(turmeric). It is a natural antioxidant and has shown many …

[HTML][HTML] Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …