Time is spine: a review of translational advances in spinal cord injury: JNSPG 75th Anniversary Invited Review Article

JH Badhiwala, CS Ahuja, MG Fehlings - Journal of Neurosurgery: Spine, 2018 - thejns.org
Acute traumatic spinal cord injury (SCI) is a devastating event with far-reaching physical,
emotional, and economic consequences for patients, families, and society at large. Timely …

MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice

J Sastre-Garriga, D Pareto, M Battaglini… - Nature Reviews …, 2020 - nature.com
Early evaluation of treatment response and prediction of disease evolution are key issues in
the management of people with multiple sclerosis (MS). In the past 20 years, MRI has …

Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

A Rowald, S Komi, R Demesmaeker, E Baaklini… - Nature medicine, 2022 - nature.com
Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease

T Milekovic, EM Moraud, N Macellari, C Moerman… - Nature Medicine, 2023 - nature.com
People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …

Generic acquisition protocol for quantitative MRI of the spinal cord

J Cohen-Adad, E Alonso-Ortiz, M Abramovic… - Nature protocols, 2021 - nature.com
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging

G David, S Mohammadi, AR Martin… - Nature Reviews …, 2019 - nature.com
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

The ANTsX ecosystem for quantitative biological and medical imaging

NJ Tustison, PA Cook, AJ Holbrook, HJ Johnson… - Scientific reports, 2021 - nature.com
Abstract The Advanced Normalizations Tools ecosystem, known as ANTsX, consists of
multiple open-source software libraries which house top-performing algorithms used …

Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks

C Gros, B De Leener, A Badji, J Maranzano, D Eden… - Neuroimage, 2019 - Elsevier
The spinal cord is frequently affected by atrophy and/or lesions in multiple sclerosis (MS)
patients. Segmentation of the spinal cord and lesions from MRI data provides measures of …

PAM50: Unbiased multimodal template of the brainstem and spinal cord aligned with the ICBM152 space

B De Leener, VS Fonov, DL Collins, V Callot, N Stikov… - Neuroimage, 2018 - Elsevier
Template-based analysis of multi-parametric MRI data of the spinal cord sets the foundation
for standardization and reproducibility, thereby helping the discovery of new biomarkers of …

MRI in traumatic spinal cord injury: from clinical assessment to neuroimaging biomarkers

P Freund, M Seif, N Weiskopf, K Friston… - The Lancet …, 2019 - thelancet.com
Traumatic spinal cord injury occurs when an external physical impact damages the spinal
cord and leads to permanent neurological dysfunction and disability, and it is associated …