Abstract cGMP controls many cellular functions ranging from growth, viability, and
differentiation to contractility, secretion, and ion transport. The mammalian genome encodes …

Natriuretic peptides are a family of structurally related but genetically distinct
hormones/paracrine factors that regulate blood volume, blood pressure, ventricular …

Since the discovery in 1957 that cyclic AMP acts as a second messenger for the hormone
adrenaline, interest in this molecule and its companion, cyclic GMP, has grown. Over a …

To elucidate the ligand-receptor relationship of the natriuretic peptide system, which
comprises at least three endogenous ligands, atrial natriuretic peptide (ANP), brain …

A MAJOR mechanism by which insulin stimulates glucose transport in muscle and fat is the
translocation of glucose transporters from an intracellular membrane pool to the cell …

ATRIAL natriuretic peptide (ANP) is a polypeptide hormone whose effects include the
induction of diuresis, natriuresis and vasorelaxation1. One of the earliest events following …

Nitric Oxide and Cyclic GMP in Cell Signaling and Drug Development | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Endopeptidase-24.11 (E-24.11, EC 3.4. 24.11) is widely believed to play a physiological role
in metabolizing atrial natriuretic peptide (ANP). Since the discovery of ANP, new natriuretic …

The role of nitric oxide in cellular signaling in the past 22 years has become one of the most
rapidly growing areas in biology with more than 20,000 publications to date. Nitric oxide is a …

The major class of atrial natriuretic peptide (ANP) receptors was isolated from cultured
vascular smooth muscle cells, and a partial amino acid sequence was obtained. This …