Efficient activation of neutrophils is a key requirement for effective immune responses. We
found that neutrophils released cellular adenosine triphosphate (ATP) in response to …

Background Leishmaniasis, a parasitic disease caused by protozoa of the genus
Leishmania, affects more than 12 million people worldwide. Quercetin has generated …

African trypanosomosis is a chronic debilitating disease affecting the health and economic
well‐being of developing countries. The immune response during African trypanosome …

Nucleoside triphosphate diphosphohydrolases (NTPDases, GDA1_CD39 protein
superfamily) play a diverse range of roles in a number of eukaryotic organisms. In humans …

Trypanosoma cruzi, the protozoan responsible for Chagas disease, has a complex life cycle
comprehending two distinct hosts and a series of morphological and functional …

Hydroperoxide detoxification in African trypanosomes is achieved by 2-Cys-peroxiredoxin
(TXNPx)-and non-selenium glutathione peroxidase (Px)-type enzymes which both obtain …

Leishmania amazonensis is a protozoan parasite that occurs in many areas of Brazil and
causes skin lesions. Using this parasite, our group showed the activation of Na+/K+ ATPase …

The year 2009 is the centennial anniversary of the original description of Chagas disease by
Carlos Chagas. During the last 100 years, several advances have occurred regarding our …

In the present paper we studied the involvement of the phosphatidylinositol-specific PLC (PI-
PLC)/protein kinase C (PKC) pathway in (Na++ K+) ATPase stimulation by heme in …

A leishmaniose ainda é uma das doenças mais negligenciadas do mundo. Ela está
presente nos cinco continentes e é endêmica em 98 países, com 350 milhões de pessoas …