Background Treatment of brain tumors, epilepsy, or hemodynamic abnormalities requires a
craniotomy to access the brain. Nearly 1 million craniotomies are performed in the US …

Vaccination arguably remains the only long-term strategy to limit the spread of S. aureus
infections and its related antibiotic resistance. To date, however, all staphylococcal vaccines …

The early immune response to bacterial pneumonia requires a careful balance between
pathogen clearance and tissue damage. The anti-inflammatory cytokine interleukin (IL)-10 is …

Staphylococcus aureus propensity for intracellular survival presents a challenge to
effectively treat infection, with significant evidence suggesting S. aureus can hijack …

Staphylococcus aureus is a leading cause of medical device-associated biofilm infections.
This is influenced by the ability of S. aureus biofilm to evade the host immune response …

Atopic dermatitis (AD) is an inflammatory skin condition with a childhood prevalence of up to
25%. Microbial dysbiosis is characteristic of AD, with Staphylococcus aureus the most …

Staphylococcus aureus can lead to chronic infections and abscesses in internal organs
including kidneys, which are associated with the expansion of myeloid-derived suppressor …

Staphylococcus aureus is a significant cause of morbidity and mortality in pulmonary
infections. Patients with autosomal-dominant hyper-IgE syndrome due to STAT3 deficiency …

Multiple sclerosis (MS) is a chronic progressive autoimmune disease of the central nervous
system (CNS). MS is characterised by the presence of demyelinating lesions in the CNS and …

Background: Lower respiratory tract infection (LRTI) is a leading cause of infant morbidity
and mortality globally. LRTI may be caused by viral or bacterial infections, individually or in …