Bone metastasis, a prevalent occurrence in primary malignant tumors, is often associated
with a grim prognosis. The bone microenvironment comprises various coexisting cell types …

Bone diseases including osteoarthritis, osteoporosis, and bone tumors are becoming severe
threats to public health. Bone-targeted biomaterials-based strategies could improve …

Bones provide essential functions and are sites of unique biochemistry and specialized
cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has …

Hematological malignancies (HM) are a collection of malignant transformations originating
from cells in the primary or secondary lymphoid organs. Leukemia, lymphoma, and multiple …

Nanotechnology is a vigorous research area and one of its important applications is in
biomedical sciences. Among biomedical applications, targeted drug delivery is one of the …

We present the synthesis of a silver nanoparticle (AgNP) based drug-delivery system that
achieves the simultaneous intracellular delivery of doxorubicin (Dox) and alendronate (Ald) …

Biomaterials are commonly applied in regenerative therapy and tissue engineering in bone,
and have been substantially refined in recent years. Thereby, research approaches focus …

Simple Summary Bone represents a common metastatic site for patients with advanced
cancers while also being associated with rare but challenging primary tumors. As the …

Delivery of therapeutic agents to bone is crucial in several diseases such as osteoporosis,
Paget's disease, myeloproliferative diseases, multiple myeloma as well as skeletal …

An aging population in the developing world has led to an increase in musculoskeletal
diseases such as osteoporosis and bone metastases. Left untreated many bone diseases …