Molecular characteristics and functional analysis of non-specific cytotoxic cell receptor (NCCRP1) in golden pompano (Trachinotus ovatus)

M Huang, Z Zhang, X Li, J Feng, Y Huang… - Fish & Shellfish …, 2024 - Elsevier
Non-specific cytotoxic cells (NCCs) are cytotoxic cell population found in innate immune
system of teleost, playing crucial role in immune defense. Non-specific cytotoxic cell receptor …

Medulla oblongata and NCCs are central defenders against Streptococcus agalactiae infection of the tilapia brain

X Hou, Q Li - Frontiers in Immunology, 2024 - frontiersin.org
Various types of professional immune cells first emerge in fish and likely represent the
primordial form and functions. Recent advancements revealed the direct connection …

Novel C-type lectin mediated non-specific cytotoxic cells killing activity through NCCRP-1 in nile tilapia (Oreochromis niloticus)

Y Huang, Z Chen, J Zhang, K Amoah, B Asiedu… - Fish & Shellfish …, 2024 - Elsevier
Non-specific cytotoxic cells (NCCs) are vital immune cells involved in teleost's non-specific
immunity. As a receptor molecule on the NCCs' surface, the non-specific cytotoxic cell …

Distribution and response strategies of non-specific cytotoxic cell receptor protein 1 in large yellow croaker

Y Yao, Q Li, Q Yan - Fish & Shellfish Immunology, 2024 - Elsevier
The non-specific cytotoxic cell receptor protein 1 (NCCRP1) is considered the universal
marker for teleost non-specific cytotoxic cells (NCCs). However, the specific distribution …

Costimulatory Molecules CD80/86 Trigger Non-Specific Cytotoxic Cell of Nile tilapia (Oreochromis niloticus) to Kill CIK Cells

Y Huang, Z Chen, R Xie, K Amoah, B Wang, J Cai, Y Lu… - Fishes, 2022 - mdpi.com
The teleost non-specific cytotoxic cell (NCC), as the evolutionary precursors of NK cells, is
an important cytotoxic cell population in the innate immune system of teleost. We have …