Immune influencers in action: metabolites and enzymes of the tryptophan-kynurenine metabolic pathway

M Tanaka, F Tóth, H Polyák, Á Szabó, Y Mándi… - Biomedicines, 2021 - mdpi.com
The tryptophan (TRP)-kynurenine (KYN) metabolic pathway is a main player of TRP
metabolism through which more than 95% of TRP is catabolized. The pathway is activated …

A review of cytokine-based pathophysiology of Long COVID symptoms

RN Low, RJ Low, A Akrami - Frontiers in Medicine, 2023 - frontiersin.org
The Long COVID/Post Acute Sequelae of COVID-19 (PASC) group includes patients with
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …

Factors related to mental health of inpatients with COVID-19 in Wuhan, China

Y Hu, Y Chen, Y Zheng, C You, J Tan, L Hu… - Brain, behavior, and …, 2020 - Elsevier
Objective To evaluate the mental health status of hospitalized patients with coronavirus
disease 2019 (COVID-19) and to explore the related factors. Method This was a cross …

On inflammatory hypothesis of depression: what is the role of IL-6 in the middle of the chaos?

E Roohi, N Jaafari, F Hashemian - Journal of neuroinflammation, 2021 - Springer
Many patients with major depressive disorder (MDD) are reported to have higher levels of
multiple inflammatory cytokines including interleukin 6 (IL-6). Recent studies both pre …

[HTML][HTML] The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacological treatment

EJ van Vuren, SF Steyn, CB Brink, M Möller… - Biomedicine & …, 2021 - Elsevier
The recent outbreak of the corona virus disease (COVID-19) has had major global impact.
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …

Anxiolytic and antidepressive potentials of rosmarinic acid: A review with a focus on antioxidant and anti-inflammatory effects

A Dahchour - Pharmacological Research, 2022 - Elsevier
Depression and anxiety are the most prevalent neuropsychiatric disorders that have
emerged as global health concerns. Anxiolytic and antidepressant drugs, such as …

[HTML][HTML] Persistence of long COVID symptoms in COVID-19 survivors worldwide and its potential pathogenesis-a systematic review and meta-analysis

M Fahriani, M Ilmawan, JK Fajar, HA Maliga… - Narra J, 2021 - ncbi.nlm.nih.gov
The study sought to determine the prevalence of persistent long COVID symptoms such as
anxiety, depression, dizziness, chest pain, sleep difficulty, palpitations, weight loss, and hair …

Palmitoylethanolamide: a natural compound for health management

P Clayton, M Hill, N Bogoda, S Subah… - International journal of …, 2021 - mdpi.com
All nations which have undergone a nutrition transition have experienced increased
frequency and falling latency of chronic degenerative diseases, which are largely driven by …

The association between anxiety, traumatic stress, and obsessive–compulsive disorders and chronic inflammation: A systematic review and meta‐analysis

ME Renna, MS O'Toole, PE Spaeth… - Depression and …, 2018 - Wiley Online Library
Background Anxiety is characterized by prolonged preparation for real or perceived threat.
This may manifest both as psychological and physiological activation, ultimately leading to …

Systematic review and meta-analysis of the association between peripheral inflammatory cytokines and generalised anxiety disorder

H Costello, RL Gould, E Abrol, R Howard - BMJ open, 2019 - bmjopen.bmj.com
Objective Inflammation has been implicated in the aetiology of mental illness. We conducted
the first systematic review and meta-analysis of the association between peripheral markers …