Gene therapies are designed to address the root cause of disease. As scientific
understanding of disease prevention, diagnosis, and treatment improves in tandem with …

There is an urgent need to develop a strategy for curative options for sickle cell disease
(SCD) in Africa as this is a disease of public health significance. It is common [84% of 14 …

Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …

Background Sickle cell disease (SCD) is a recognized cause of childhood mortality.
Tanzania has the fifth highest incidence of SCD (with an estimated 11 000 SCD annual …

Rare diseases (RD) pose serious challenges in terms of both diagnosis and treatment.
Legislation was passed in the US (1983) and in EU (2000) aimed to reverse the previous …

2. Bizri AR, Khachfe HH, Fares MY, Musharrafieh U. COVID-19 pandemic: an insult over
injury for Lebanon. J Community Health. 2020. https://doi. org/10.1007/s10900-020-00884 …

Objective To determine the regional-and district-level newborn prevalence of sickle cell trait
and disease, and the prevalence of haemoglobin variants and genetic modifiers of sickle …

Factors contributing to low use of HU among SCD patients exist in high-income countries.
The latter leaves a drift of literature on factors for low utilization of HU in developing …

Tanzania is among the top five countries with a high burden of sickle cell disease (SCD) in
the world. Even though the effects of SCD on quality of life have been documented in other …

Sickle Cell Disease (SCD) is a known public health burden in sub-Saharan Africa (SSA).
The manifestation of SCD starts in early childhood and if not well-managed may lead to …