Oxidative stress and reactive oxygen species: a review of their role in ocular disease
For many years, oxidative stress arising from the ubiquitous production of reactive oxygen
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …
Biofilms in infections of the eye
PJM Bispo, W Haas, MS Gilmore - Pathogens, 2015 - mdpi.com
The ability to form biofilms in a variety of environments is a common trait of bacteria, and
may represent one of the earliest defenses against predation. Biofilms are multicellular …
may represent one of the earliest defenses against predation. Biofilms are multicellular …
Vision defense: Efficient antibacterial AIEgens induced early immune response for bacterial endophthalmitis
T Li, Y Wu, W Cai, D Wang, C Ren, T Shen… - Advanced …, 2022 - Wiley Online Library
Bacterial endophthalmitis (BE) is an acute eye infection and potentially irreversible blinding
ocular disease. The empirical intravitreous injection of antibiotic is the primary treatment …
ocular disease. The empirical intravitreous injection of antibiotic is the primary treatment …
Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection
The eye is highly susceptible to inflammation-mediated tissue damage evoked during
bacterial infection. However, mechanisms regulating inflammation to protect the eye remain …
bacterial infection. However, mechanisms regulating inflammation to protect the eye remain …
An Eye on Staphylococcus aureus Toxins: Roles in Ocular Damage and Inflammation
R Astley, FC Miller, MH Mursalin, PS Coburn… - Toxins, 2019 - mdpi.com
Staphylococcus aureus (S. aureus) is a common pathogen of the eye, capable of infecting
external tissues such as the tear duct, conjunctiva, and the cornea, as well the inner and …
external tissues such as the tear duct, conjunctiva, and the cornea, as well the inner and …
Muller glia in retinal innate immunity: a perspective on their roles in endophthalmitis
Muller cells are the predominant glial cell type in the retina and have a unique anatomy, with
processes that span the entire retinal thickness. Although extensive morphological and …
processes that span the entire retinal thickness. Although extensive morphological and …
Intravitreal injection of the chimeric phage endolysin Ply187 protects mice from Staphylococcus aureus endophthalmitis
The treatment of endophthalmitis is becoming very challenging due to the emergence of
multidrug-resistant bacteria. Hence, the development of novel therapeutic alternatives for …
multidrug-resistant bacteria. Hence, the development of novel therapeutic alternatives for …
Gallium-Based Nanoplatform for Combating Multidrug-Resistant Pseudomonas aeruginosa and Postoperative Inflammation in Endophthalmitis Secondary to …
Y Qiao, Y Li, Y Ye, Y Yu, W Wang, K Yao… - ACS Applied Materials …, 2022 - ACS Publications
Postcataract endophthalmitis (PCE), a devastating complication following cataract surgeries,
is one of the most crucial diseases causing irreversible eye blindness. Pseudomonas …
is one of the most crucial diseases causing irreversible eye blindness. Pseudomonas …
Adjunctive steroid therapy versus antibiotics alone for acute endophthalmitis after intraocular procedure
S Emami, K Kitayama… - Cochrane Database of …, 2022 - cochranelibrary.com
Background Endophthalmitis refers to severe infection within the eye that involves the
aqueous humor or vitreous humor, or both, and that threatens vision. Most cases of …
aqueous humor or vitreous humor, or both, and that threatens vision. Most cases of …
Role of Staphylococcus aureus Virulence Factors in Inducing Inflammation and Vascular Permeability in a Mouse Model of Bacterial Endophthalmitis
Staphylococcus (S.) aureus is a common causative agent of bacterial endophthalmitis, a
vision threatening complication of eye surgeries. The relative contribution of S. aureus …
vision threatening complication of eye surgeries. The relative contribution of S. aureus …