Scaling up genetic circuit design for cellular computing: advances and prospects

Y Xiang, N Dalchau, B Wang - Natural computing, 2018 - Springer
Synthetic biology aims to engineer and redesign biological systems for useful real-world
applications in biomanufacturing, biosensing and biotherapy following a typical design-build …

[HTML][HTML] Design of an embedded inverse-feedforward biomolecular tracking controller for enzymatic reaction processes

M Foo, J Kim, R Sawlekar, DG Bates - Computers & Chemical Engineering, 2017 - Elsevier
Feedback control is widely used in chemical engineering to improve the performance and
robustness of chemical processes. Feedback controllers require a 'subtractor'that is able to …

[PDF][PDF] Investigating the Efficacy of Nanopore-Addressable Protein Tags as Reporters in Genetic Circuits

CG Thompson - 2024 - research-information.bris.ac.uk
Over the past few decades, huge leaps have been made in the complexity of engineered
genetic circuits, as well as the ease with which they can be assembled. However, for them to …

Engineering complexity in bacterial regulatory circuits for biotechnological applications

CA Westmann, ME Guazzaroni, R Silva-Rocha - Msystems, 2018 - Am Soc Microbiol
Engineering microbial systems allows the generation of new technologies having significant
impact in the biotechnological industry and on human health. In the past few years, several …

Retroactivity induced operating regime transition in a phosphorylation-dephosphorylation cycle

A Parundekar, GA Viswanathan - bioRxiv, 2020 - biorxiv.org
Operating regimes characterizing the input-output behaviour of an activated phosphorylation-
dephosphorylation reaction cycle (PdPC) such as a single MAPK cascade are dictated by …