Intermediate filaments constitute the third component of the cellular skeleton. Unlike actin
and microtubule cytoskeletons, the intermediate filaments are composed of a wide variety of …

Intermediate filaments (IFs) are one of the three major elements of the cytoskeleton. Their
stability, intrinsic mechanical properties, and cell type–specific expression patterns …

The keratin network of intermediate filaments provides keratinocytes with essential
mechanical strength and resilience, but the contribution to mechanosensing remains poorly …

Mesenchymal cell migration relies on the coordinated regulation of the actin and
microtubule networks that participate in polarized cell protrusion, adhesion, and contraction …

Cell adhesion to the extracellular matrix is essential for cellular processes, such as migration
and invasion. In response to cues from the microenvironment, integrin-mediated adhesions …

Vimentin, a kind of intermediate filament protein III in mesenchymal cells, has become a
highly researched topic around the world in recent years, as it holds complex biological …

The cytoskeleton determines cell mechanics and lies at the heart of important cellular
functions. Growing evidence suggests that the manifold tasks of the cytoskeleton rely on the …

Cell migration is a vital and dynamic process required for the development of multicellular
organisms and for immune system responses, tissue renewal and wound healing in adults. It …

Millions of people die from liver diseases annually, and liver failure is one of the three major
outcomes of liver disease. The gut microbiota plays a crucial role in liver diseases. This …

Glial fibrillary acidic protein (GFAP) is an intermediate filament protein that is characteristic
for astrocytes and neural stem cells, and their malignant analogues in glioma. Since the …