Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
[HTML][HTML] Cancer associated-fibroblast-derived exosomes in cancer progression
To identify novel cancer therapies, the tumor microenvironment (TME) has received a lot of
attention in recent years in particular with the advent of clinical successes achieved by …
attention in recent years in particular with the advent of clinical successes achieved by …
[HTML][HTML] Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine
The first two mRNA vaccines against infection by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) that were approved by regulators require a cold chain and …
coronavirus 2 (SARS-CoV-2) that were approved by regulators require a cold chain and …
[HTML][HTML] Inhalable dry powder mRNA vaccines based on extracellular vesicles
Respiratory diseases are a global burden, with millions of deaths attributed to pulmonary
illnesses and dysfunctions. Therapeutics have been developed, but they present major …
illnesses and dysfunctions. Therapeutics have been developed, but they present major …
[HTML][HTML] Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by
cells, and play a role in intercell communication and disease development. The Global …
cells, and play a role in intercell communication and disease development. The Global …
[HTML][HTML] Principles and problems of exosome isolation from biological fluids
EI Yakubovich, AG Polischouk… - … ), Supplement Series A …, 2022 - Springer
Exosomes, the subclass of small membrane extracellular vesicles, have great diagnostic
and therapeutic potential, but the lack of standardized methods for their efficient isolation …
and therapeutic potential, but the lack of standardized methods for their efficient isolation …
[HTML][HTML] Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers
N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …
of therapeutic applications due to their unique characteristics, especially due to the …
[HTML][HTML] Inhalable exosomes outperform liposomes as mRNA and protein drug carriers to the lung
KD Popowski, BL de Juan Abad, A George… - Extracellular …, 2022 - Elsevier
Respiratory diseases are among the leading causes of morbidity and mortality worldwide,
coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic. mRNA lipid …
coupled with the ongoing coronavirus disease 2019 (COVID-19) pandemic. mRNA lipid …
Therapeutic effects of bone marrow mesenchymal stem cells‐derived exosomes on osteoarthritis
Y Jin, M Xu, H Zhu, C Dong, J Ji, Y Liu… - Journal of cellular …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) have shown chondroprotective effects in clinical models of
osteoarthritis (OA). However, effects of MSC‐derived exosomes on OA remain unclear. The …
osteoarthritis (OA). However, effects of MSC‐derived exosomes on OA remain unclear. The …
[HTML][HTML] Exosome-based drug delivery systems and their therapeutic applications
In the past few decades, scientists have actively worked on developing effective drug
delivery systems (DDSs) as means to control life-threatening diseases and challenging …
delivery systems (DDSs) as means to control life-threatening diseases and challenging …