Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …

The microbiota of solid tumors was identified> 100 years ago; however, heterogeneous
composition and diversity have been revealed only recently. Growing evidence has …

Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

The intricate interplay between the gut microbiome and colorectal cancer (CRC) presents
novel avenues for early diagnosis and prognosis, crucial for improving patient outcomes …

Colorectal cancer (CRC) is a common malignancy of the gastrointestinal tract, accounting for
the second most common cause of gastrointestinal tumors. As one of the intestinal barriers …

Intestinal flora affects the maturation of the host immune system, serves as a biomarker and
efficacy predictor in the immunotherapy of several cancers, and has an important role in the …

Colorectal cancer (CRC) is one of the most prevalent and lethal malignant tumors globally,
posing significant health risks and societal burdens. Recently, advancements in next …

Colorectal cancer (CRC), a prevalent global malignancy, often necessitates adjuvant
therapies such as chemotherapy, radiotherapy, targeted therapy, and immunotherapy to …

Background Fatty acids synthesis and metabolism (FASM)-driven lipid mobilization is
essential for energy production during nutrient shortages. However, the molecular …

Abstract Purpose of Review This review will explore various strategies to rendering MSS
mCRCs susceptible to ICI. Moreover, we will provide an overview of potential biomarkers …