Glucagon‐like peptide agonists: A prospective review

Z Mariam, SK Niazi - Endocrinology, Diabetes & Metabolism, 2024 - Wiley Online Library
Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have emerged as
promising therapeutic options for addressing Type‐2 diabetes, obesity, and related …

[HTML][HTML] Efficacy of liraglutide in obesity in children and adolescents: systematic review and meta-analysis of randomized controlled trials

A Cornejo-Estrada, C Nieto-Rodriguez… - Children, 2023 - mdpi.com
In the past few decades, childhood obesity has become a significant global health issue,
impacting around 107.7 million children and adolescents globally. There is currently minimal …

[HTML][HTML] Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma

ECN Lawrence, M Guo, TD Schwartz, J Wu… - Frontiers in Cellular …, 2023 - frontiersin.org
Glaucomatous neurodegeneration, a blinding disease affecting millions worldwide, has a
need for the exploration of new and effective therapies. Previously, the glucagon-like …

[HTML][HTML] Does Therapy with Glucagon-like Peptide 1 Receptor Agonists Have an Effect on Biochemical Markers of Metabolic-Dysfunction-Associated Steatotic Liver …

M Hachuła, M Kosowski, M Basiak, B Okopień - Pharmaceuticals, 2023 - mdpi.com
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) is associated with the
excessive collection of lipids in hepatocytes. Over 75% of diabetes patients typically have …

[HTML][HTML] GLP-1 receptor agonists for weight reduction in people living with obesity but without diabetes: a living benefit–harm modelling study

H Moll, E Frey, P Gerber, B Geidl, M Kaufmann… - …, 2024 - thelancet.com
Summary Background The benefit of Glucagon-like Peptide-1 (GLP-1) receptor agonists
(RAs) in weight reduction against potential harms remains unclear. This study aimed at …

Effectiveness and safety of drugs for obesity

K Henderson, CE Sloan, DH Bessesen, D Arterburn - bmj, 2024 - bmj.com
Recent publicity around the use of new antiobesity medications (AOMs) has focused the
attention of patients and healthcare providers on the role of pharmacotherapy in the …

[HTML][HTML] From Diabetes to Oncology: Glucagon-like Peptide-1 (GLP-1) Receptor Agonist's Dual Role in Prostate Cancer

A Alhajahjeh, R Al-Faouri, HF Bahmad, T Bader… - Cancers, 2024 - mdpi.com
Simple Summary In this review paper, we outline the role of GLP-1-RAs in potentially
influencing PCa development and progression. While GLP-1-RAs show promise in inhibiting …

[HTML][HTML] Hunger & satiety signals: another key mechanism involved in the NAFLD pathway

I López-Méndez, ADC Maldonado-Rojas… - Frontiers in …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent metabolic disease, although
prevalence could change according to region, nowadays is considered a public health …

Liraglutide 3.0 mg in the treatment of adults with obesity and prediabetes using real‐world UK data: A clinical evaluation of a multi‐ethnic population

LJ Dobbie, C Coelho, F Mgaieth, K Chauhan… - Clinical …, 2024 - Wiley Online Library
UK guidelines recommend liraglutide 3.0 mg in adults treated within specialist weight
management services with BMI≥ 35 kg/m2, prediabetes and high cardiovascular disease …

[PDF][PDF] Cost-effectiveness analysis of once-weekly semaglutide vs. once-daily liraglutide administered subcutaneously in patients with overweight and obesity: a …

M Alshahawey, M Ghazy… - European Review for …, 2024 - europeanreview.org
OBJECTIVE: Obesity presents an enduring and multifaceted dilemma that impacts
individuals, society, economies, and healthcare systems alike. Glucagon-like peptide-1 …