Hand-foot-and-mouth disease (HFMD) is a viral illness commonly seen in young children
under 5 years of age, characterized by typical manifestations such as oral herpes and …

Enteroviruses (EV) can cause severe neurological and respiratory infections, and
occasionally lead to devastating outbreaks as previously demonstrated with EV-A71 and EV …

Abstract Enterovirus A71 (EV-A71) is one of the common causative pathogens for hand foot
and mouth disease (HFMD) affecting young children. HFMD outbreak can result in a …

Summary Background In May, 2018, Children's Hospital Colorado noted an outbreak of
enterovirus A71 (EV-A71) neurological disease. We aimed to characterise the clinical …

Background Acute flaccid myelitis (AFM) is an acute flaccid paralysis syndrome with spinal
motor neuron involvement of unknown etiology. We investigated the characteristics and …

As a neurotropic virus, human Enterovirus 71 (EV71) infection causes hand-foot-and-mouth
disease (HFMD) and may develop severe neurological disorders in infants. Toll-like receptor …

Enterovirus 71 (EV71) infections have a major public health impact in the Asia-Pacific
region. We reviewed the epidemiology, pathogenesis, and molecular epidemiology of EV71 …

Mechanical ventilation (MV) is an essential part of modern intensive care medicine. MV is
performed in patients with severe respiratory failure caused by respiratory muscle …

Background Encephalitis is a worldwide public health issue, with a substantially high burden
among children in southeast Asia. We aimed to determine the causes of encephalitis in …

Seizures are a common presenting symptom during viral infections of the central nervous
system (CNS) and can occur during the initial phase of infection (“early” or acute …