Hyaluronic Acid‐Based Bioconjugate Systems, Scaffolds, and Their Therapeutic Potential

NG Kotla, IL Mohd Isa, A Larrañaga… - Advanced …, 2023 - Wiley Online Library
In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds,
medical devices, bioconjugate systems have expanded into a broad range of research and …

[HTML][HTML] Hyaluronic acid: A review of the drug delivery capabilities of this naturally occurring polysaccharide

C Buckley, EJ Murphy, TR Montgomery, I Major - Polymers, 2022 - mdpi.com
The inclusion of physiologically active molecules into a naturally occurring polymer matrix
can improve the degradation, absorption, and release profile of the drug, thus boosting the …

[HTML][HTML] Effect of crosslinking strategy on the biological, antibacterial and physicochemical performance of hyaluronic acid and ɛ-polylysine based hydrogels

K Salma-Ancane, A Sceglovs, E Tracuma… - International Journal of …, 2022 - Elsevier
The design of multifunctional hydrogels based on bioactive hyaluronic acid (HA) and
antibacterial cationic polymer ɛ-poly-l-lysine (ε-PL) is a promising tool in tissue engineering …

Chemical modification of hyaluronic acid as a strategy for the development of advanced drug delivery systems

AN Bokatyi, NV Dubashynskaya, YA Skorik - Carbohydrate Polymers, 2024 - Elsevier
Hyaluronic acid (HA) has emerged as a promising biopolymer for various biomedical
applications due to its biocompatibility, biodegradability, and intrinsic ability to interact with …

Synthesis, characterization, and in vitro anti-tumor activity studies of the hyaluronic acid-mangiferin-methotrexate nanodrug targeted delivery system

H Wang, W Shao, X Lu, C Gao, L Fang, X Yang… - International Journal of …, 2023 - Elsevier
In this study, to increase the accumulation of MTX in the tumor site and reduce the toxicity to
normal tissues by MA, a novel nano-drug delivery system comprised of hyaluronic acid (HA) …

[HTML][HTML] Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes

S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

[HTML][HTML] Enhancing intradermal delivery of lidocaine by dissolving microneedles: comparison between hyaluronic acid and poly (vinyl pyrrolidone) backbone polymers

D Ramadon, LFP Sutrisna, Y Harahap, KSS Putri… - Pharmaceutics, 2023 - mdpi.com
Lidocaine hydrochloride (LiH), an amide-type local anesthetic agent, is commonly used in
dermatological procedures. LiH is categorized as a BCS (biopharmaceutics classification …

[HTML][HTML] Advances in functionalization of bioresorbable nanomembranes and nanoparticles for their use in biomedicine

AHM Mohammed-Sadhakathullah… - International Journal of …, 2023 - mdpi.com
Bioresorbable nanomembranes (NMs) and nanoparticles (NPs) are powerful polymeric
materials playing an important role in biomedicine, as they can effectively reduce infections …

The role of hyaluronic acid in the design and functionalization of nanoparticles for the treatment of colorectal cancer

MC de Paula, SG Carvalho, ALP Silvestre… - Carbohydrate …, 2023 - Elsevier
Despite advances in new approaches for colorectal cancer (CRC) therapy, intravenous
chemotherapy remains one of the main treatment options; however, it has limitations …

[HTML][HTML] Peripheralized sepiapterin reductase inhibition as a safe analgesic therapy

SJF Cronin, NA Andrews, A Latremoliere - Frontiers in Pharmacology, 2023 - frontiersin.org
The development of novel analgesics for chronic pain in the last 2 decades has proven
virtually intractable, typically failing due to lack of efficacy and dose-limiting side effects …