Macrophage activation-like syndrome: a distinct entity leading to early death in sepsis

E Karakike, EJ Giamarellos-Bourboulis - Frontiers in immunology, 2019 - frontiersin.org
Hemophagocytic lymphohistocytosis (HLH) is characterized by fulminant cytokine storm
leading to multiple organ dysfunction and high mortality. HLH is classified into familial …

Treatment and mortality of hemophagocytic lymphohistiocytosis in adult critically ill patients: a systematic review with pooled analysis

C Knaak, FS Schuster, P Nyvlt, C Spies… - Critical care …, 2020 - journals.lww.com
Objectives: Hemophagocytic lymphohistiocytosis is a cytokine release syndrome caused by
uncontrolled immune activation resulting in multiple organ failure and death. In this …

Hemophagocytic lymphohistiocytosis

J Skinner, B Yankey, BK Shelton - AACN advanced critical care, 2019 - AACN
Hemophagocytic lymphohistiocytosis is a life-threatening condition associated with
hyperinflammation and multiple organ dysfunction. It has many causes, symptoms, and …

A novel prognostic model for adult patients with hemophagocytic lymphohistiocytosis

J Zhou, J Zhou, ZQ Wu, H Goyal, HG Xu - Orphanet Journal of Rare …, 2020 - Springer
Abstract Background Hemophagocytic Lymphohistiocytosis (HLH) is a type of rare disease
with low survival rate. We aimed to develop a model to evaluate the six-month prognosis in …

Four biomarkers linked to activation of cluster of differentiation 8–positive lymphocytes predict clinical outcomes in pediatric acute liver failure

MA Leonis, AG Miethke, L Fei, S Maynor… - …, 2021 - Wiley Online Library
Background and Aims Immune dysregulation contributes to the pathogenesis of pediatric
acute liver failure (PALF). Our aim was to identify immune activation markers (IAMs) in PALF …

Clinical characteristics of liver failure with hemophagocytic lymphohistiocytosis

J Dong, F Xie, L Jia, J Li, Z Hu, Y Zhu, H Yu, Y Zhao… - Scientific reports, 2019 - nature.com
Liver failure with hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome
with high mortality. The aim of this study was to decipher clinical and laboratory …

Liver Dysfunction in Adult Hemophagocytic Lymphohistiocytosis: A Narrative Review

M Masood, A Siddique, R Krishnamoorthi… - Advances in …, 2024 - Springer
Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition that has
been increasingly recognized in adults and is characterized by a hyperinflammatory state …

[HTML][HTML] Acute liver failure secondary to severe systemic disease from fatal hemophagocytic lymphohistiocytosis: Case report and systematic literature review

MS Cappell, I Hader, M Amin - World journal of hepatology, 2018 - ncbi.nlm.nih.gov
AIM To systematically review liver disease associated with hemophagocytic
lymphohistiocytosis (HLH), propose reasonable contraindications for liver transplantation for …

Hepatic involvement in hemophagocytic lymphohistiocytosis

S Padhi, R Sarangi, S Patra… - Hepatitis A and Other …, 2020 - books.google.com
Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome which results
in uncontrolled systemic proliferation of benign macrophages in all reticuloendothelial …

Clinical features of hepatic manifestations among adult patients with hemophagocytic lymphohistiocytosis: a retrospective study

Q Bao, Z Xu, F Yang, J Lu - Acta haematologica, 2024 - karger.com
Liver dysfunction is common in patients with hemophagocytic lymphohistiocytosis (HLH).
However, whether the severity of liver injury is associated with the prognosis of patients with …