The role of SVZ stem cells in glioblastoma

C Altmann, S Keller, MHH Schmidt - Cancers, 2019 - mdpi.com
As most common primary brain cancer, glioblastoma is also the most aggressive and
malignant form of cancer in the adult central nervous system. Glioblastomas are genetic and …

The subventricular zone in glioblastoma: Genesis, maintenance, and modeling

J Beiriger, A Habib, N Jovanovich, CV Kodavali… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma (GBM) is a malignant tumor with a median survival rate of 15-16 months with
standard care; however, cases of successful treatment offer hope that an enhanced …

[HTML][HTML] Role and mechanism of neural stem cells of the subventricular zone in glioblastoma

GL Zhang, CF Wang, C Qian, YX Ji… - World journal of stem …, 2021 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM), the most frequently occurring malignant brain tumor in
adults, remains mostly untreatable. Because of the heterogeneity of invasive gliomas and …

Adverse prognosis of glioblastoma contacting the subventricular zone: Biological correlates

S Berendsen, E Van Bodegraven, T Seute… - PloS one, 2019 - journals.plos.org
Introduction The subventricular zone (SVZ) in the brain is associated with gliomagenesis
and resistance to treatment in glioblastoma. In this study, we investigate the prognostic role …

Fibrinogen in the glioblastoma microenvironment contributes to the invasiveness of brain tumor‐initiating cells

L Dzikowski, R Mirzaei, S Sarkar, M Kumar… - Brain …, 2021 - Wiley Online Library
Glioblastomas (GBMs) are highly aggressive, recurrent, and lethal brain tumors that are
maintained via brain tumor‐initiating cells (BTICs). The aggressiveness of BTICs may be …

Alpha 1-antichymotrypsin contributes to stem cell characteristics and enhances tumorigenicity of glioblastoma

M Lara-Velazquez, N Zarco, A Carrano… - Neuro …, 2021 - academic.oup.com
Abstract Background Glioblastomas (GBMs) are the main primary brain tumors in adults with
almost 100% recurrence rate. Patients with lateral ventricle proximal GBMs (LV-GBMs) …

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

A Schuster, E Klein, V Neirinckx, AM Knudsen… - Nature …, 2020 - nature.com
The infiltrative nature of Glioblastoma (GBM), the most aggressive primary brain tumor,
critically prevents complete surgical resection and masks tumor cells behind the blood brain …

Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects

S Jain, JW Rick, RS Joshi, A Beniwal… - The Journal of …, 2023 - Am Soc Clin Investig
Cancer-associated fibroblasts (CAFs) were presumed absent in glioblastoma given the lack
of brain fibroblasts. Serial trypsinization of glioblastoma specimens yielded cells with CAF …

Nanomedicine revisited: next generation therapies for brain cancer

AG Bhargav, SK Mondal, CA Garcia… - Advanced …, 2020 - Wiley Online Library
Brain cancer persists as a difficult‐to‐treat condition. In particular, metastatic brain cancer
and malignant primary brain tumors such as glioblastoma (GBM) are among the most deadly …

Recent advances in the detection of glioblastoma, from imaging-based methods to proteomics and biosensors: A narrative review

A Hosseini, H Ashraf, F Rahimi, I Alipourfard… - Cancer Cell …, 2023 - Springer
Glioblastoma (GBM) is an aggressive type of cancer that originates in the cells called
astrocytes, which support the functioning of nerve cells. It can develop in either the brain or …