Mechanical mechanisms of chromosome segregation
MI Anjur-Dietrich, CP Kelleher, DJ Needleman - Cells, 2021 - mdpi.com
Chromosome segregation—the partitioning of genetic material into two daughter cells—is
one of the most crucial processes in cell division. In all Eukaryotes, chromosome …
one of the most crucial processes in cell division. In all Eukaryotes, chromosome …
Organization and self-assembly away from equilibrium: Toward thermodynamic design principles
M Nguyen, Y Qiu… - Annual Review of …, 2021 - annualreviews.org
Studies of biological systems and materials, together with recent experimental and
theoretical advances in colloidal and nanoscale materials, have shown how nonequilibrium …
theoretical advances in colloidal and nanoscale materials, have shown how nonequilibrium …
Euchromatin activity enhances segregation and compaction of heterochromatin in the cell nucleus
The large-scale organization of the genome inside the cell nucleus is critical for the cell's
function. Chromatin—the functional form of DNA in cells—serves as a template for active …
function. Chromatin—the functional form of DNA in cells—serves as a template for active …
Dissipation and energy propagation across scales in an active cytoskeletal material
Living systems are intrinsically nonequilibrium: They use metabolically derived chemical
energy to power their emergent dynamics and self-organization. A crucial driver of these …
energy to power their emergent dynamics and self-organization. A crucial driver of these …
Spatio-temporal patterning of extensile active stresses in microtubule-based active fluids
Microtubule-based active fluids exhibit turbulent-like autonomous flows, which are driven by
the molecular motor powered motion of filamentous constituents. Controlling active stresses …
the molecular motor powered motion of filamentous constituents. Controlling active stresses …
Light-activated microtubule-based two-dimensional active nematic
We assess the ability of two light responsive kinesin motor clusters to drive dynamics of
microtubule-based active nematics: opto-K401, a processive motor, and opto-K365, a non …
microtubule-based active nematics: opto-K401, a processive motor, and opto-K365, a non …
Pattern formation and polarity sorting of driven actin filaments on lipid membranes
A Sciortino, AR Bausch - Proceedings of the National …, 2021 - National Acad Sciences
Collective motion of active matter is ubiquitously observed, ranging from propelled colloids
to flocks of bird, and often features the formation of complex structures composed of agents …
to flocks of bird, and often features the formation of complex structures composed of agents …
Active microphase separation in mixtures of microtubules and tip-accumulating molecular motors
Mixtures of filaments and molecular motors form active materials with diverse dynamical
behaviors that vary based on their constituents' molecular properties. To develop a …
behaviors that vary based on their constituents' molecular properties. To develop a …
Toward the cellular-scale simulation of motor-driven cytoskeletal assemblies
The cytoskeleton–a collection of polymeric filaments, molecular motors, and crosslinkers–is
a foundational example of active matter, and in the cell assembles into organelles that guide …
a foundational example of active matter, and in the cell assembles into organelles that guide …
Competing instabilities reveal how to rationally design and control active crosslinked gels
How active stresses generated by molecular motors set the large-scale mechanics of the cell
cytoskeleton remains poorly understood. Here, we combine experiments and theory to …
cytoskeleton remains poorly understood. Here, we combine experiments and theory to …