Trends in the development of miRNA bioinformatics tools
L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …
recognition of cognate sequences and interference of transcriptional, translational or …
Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …
miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database
MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25
nucleotides) that negatively control expression of target genes at the post-transcriptional …
nucleotides) that negatively control expression of target genes at the post-transcriptional …
TransmiR v2. 0: an updated transcription factor-microRNA regulation database
Z Tong, Q Cui, J Wang, Y Zhou - Nucleic acids research, 2019 - academic.oup.com
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression and
play vital roles in various biological processes. It has been reported that aberrant regulation …
play vital roles in various biological processes. It has been reported that aberrant regulation …
HMDD v2. 0: a database for experimentally supported human microRNA and disease associations
Abstract The Human microRNA Disease Database (HMDD; available via the Web site at
http://cmbi. bjmu. edu. cn/hmdd and http://202.38. 126.151/hmdd/tools/hmdd2. html) is a …
http://cmbi. bjmu. edu. cn/hmdd and http://202.38. 126.151/hmdd/tools/hmdd2. html) is a …
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review
P Csermely, T Korcsmáros, HJM Kiss, G London… - Pharmacology & …, 2013 - Elsevier
Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …
methods and in rational drug design, the increase in approved drugs in the past decade did …
RegNetwork: an integrated database of transcriptional and post-transcriptional regulatory networks in human and mouse
Transcriptional and post-transcriptional regulation of gene expression is of fundamental
importance to numerous biological processes. Nowadays, an increasing amount of gene …
importance to numerous biological processes. Nowadays, an increasing amount of gene …
ChIPBase v2. 0: decoding transcriptional regulatory networks of non-coding RNAs and protein-coding genes from ChIP-seq data
The abnormal transcriptional regulation of non-coding RNAs (ncRNAs) and protein-coding
genes (PCGs) is contributed to various biological processes and linked with human …
genes (PCGs) is contributed to various biological processes and linked with human …
Bioinformatic tools for microRNA dissection
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
Hypoxia: a master regulator of microRNA biogenesis and activity
S Nallamshetty, SY Chan, J Loscalzo - Free Radical Biology and Medicine, 2013 - Elsevier
Hypoxia, or low oxygen tension, is a unique environmental stress that induces global
changes in a complex regulatory network of transcription factors and signaling proteins to …
changes in a complex regulatory network of transcription factors and signaling proteins to …