The role of molecular testing in the differential diagnosis of salivary gland carcinomas
A Skálová, G Stenman, RHW Simpson… - The American journal …, 2018 - journals.lww.com
Salivary gland neoplasms are a morphologically heterogenous group of lesions that are
often diagnostically challenging. In recent years, considerable progress in salivary gland …
often diagnostically challenging. In recent years, considerable progress in salivary gland …
Salivary gland carcinoma: novel targets to overcome treatment resistance in advanced disease
L Di Villeneuve, IL Souza, FDS Tolentino… - Frontiers in …, 2020 - frontiersin.org
Salivary gland carcinomas (SGC) account for less than 5% of head and neck malignant
neoplasms, further subcategorized in over 20 histological subtypes. For the most part …
neoplasms, further subcategorized in over 20 histological subtypes. For the most part …
[HTML][HTML] Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study
Background Systemic therapy options for salivary cancers are limited. MyPathway
(NCT02091141), a phase IIa study, evaluates targeted therapies in non-indicated tumor …
(NCT02091141), a phase IIa study, evaluates targeted therapies in non-indicated tumor …
Molecular pathology of salivary gland neoplasms: diagnostic, prognostic, and predictive perspective
MH Toper, S Sarioglu - Advances in anatomic pathology, 2021 - journals.lww.com
Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In
recent years, there has been considerable progress in efforts to reveal the molecular …
recent years, there has been considerable progress in efforts to reveal the molecular …
[HTML][HTML] The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma
No effective systemic treatment is available for patients with unresectable, recurrent, or
metastatic mucoepidermoid carcinoma (MEC), the most common salivary gland malignancy …
metastatic mucoepidermoid carcinoma (MEC), the most common salivary gland malignancy …
[HTML][HTML] Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted …
JS Ross, LM Gay, K Wang, JA Vergilio, J Suh… - Annals of …, 2017 - Elsevier
Background Relapsed/metastatic salivary gland carcinomas (SGCs) have a wide diversity of
histologic subtypes associated with variable clinical aggressiveness and response to local …
histologic subtypes associated with variable clinical aggressiveness and response to local …
Molecular biology and therapeutic targets of primitive tracheal tumors: focus on tumors derived by salivary glands and squamous cell carcinoma
Primary tracheal tumors are rare, constituting approximately 0.1–0.4% of malignant
diseases. Squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC) account for …
diseases. Squamous cell carcinoma (SCC) and adenoid cystic carcinoma (ACC) account for …
Pulmonary salivary gland tumor, mucoepidermoid carcinoma: A literature review
S Hu, J Gong, X Zhu, H Lu - Journal of Oncology, 2022 - Wiley Online Library
Pulmonary mucoepidermoid carcinoma (PMEC) is the most common malignant salivary
gland tumor in the lungs and accounts for 0.1‐0.2% of all lung malignancies in adults. It has …
gland tumor in the lungs and accounts for 0.1‐0.2% of all lung malignancies in adults. It has …
The molecular landscape of breast mucoepidermoid carcinoma
Mucoepidermoid carcinoma (MEC) of the breast is an extremely rare salivary gland‐type
tumor characterized by epidermoid, basaloid, intermediate, and/or mucinous cells arranged …
tumor characterized by epidermoid, basaloid, intermediate, and/or mucinous cells arranged …
p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
C Rodriguez-Ramirez, Z Zhang, KA Warner… - Clinical Cancer …, 2022 - AACR
Purpose: Mucoepidermoid carcinoma (MEC) is a poorly understood salivary gland
malignancy with limited therapeutic options. Cancer stem cells (CSC) are considered drivers …
malignancy with limited therapeutic options. Cancer stem cells (CSC) are considered drivers …