Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

Lipodystrophies are a heterogeneous group of congenital or acquired disorders,
characterized by partial or generalized loss of adipose tissue. Familial partial lipodystrophy …

This report of a working group established by the Japan Diabetes Society proposes a new
classification and diagnostic criteria for insulin resistance syndrome. Insulin resistance …

Lipodystrophies are a heterogeneous group of physiological changes characterized by a
selective loss of fatty tissue. Here, no fat cells are present, either through lack of …

Whereas the genetic basis of insulin sensitivity is determined by variation in multiple genes,
mutations of single genes can give rise to profound changes in such sensitivity. Mutations of …

Abstract Aims/Introduction Insulin resistance syndrome (IRS) of type A or B is triggered by
gene abnormalities of or autoantibodies to the insulin receptor, respectively. Rabson …

Introduction Insulin resistance syndrome and lipoatrophic diabetes are characterized by
severe insulin resistance and are often refractory to treatment. Trials assessing the efficacy …

Administration of an sodium–glucose cotransporter 2 inhibitor to individuals with insulin
resistance reduces the level of glucose disposal necessary to maintain glycemia as a result …

Lipodystrophies are a heterogeneous group of rare conditions characterised by the loss of
adipose tissue. The most common forms are the familial partial lipodystrophy (FPLD) …

Background Monogenic insulin resistance (IR) includes lipodystrophy and disorders of
insulin signalling. We sought to assess the effects of interventions in monogenic IR, stratified …