Advances in organ-on-a-chip materials and devices
The organ-on-a-chip (OoC) paves a way for biomedical applications ranging from preclinical
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …
Cardiovascular human organ‐on‐a‐chip platform for disease modeling, drug development, and personalized therapy
A Khanna, BP Oropeza… - Journal of Biomedical …, 2024 - Wiley Online Library
Cardiovascular organ‐on‐a‐chip (OoC) devices are composed of engineered or native
functional tissues that are cultured under controlled microenvironments inside microchips …
functional tissues that are cultured under controlled microenvironments inside microchips …
Dynamic tissue model in vitro and its application for assessment of microplastics-induced toxicity to air-blood barrier (ABB)
The replication of the hominine physiological environment was identified as an effectual
strategy to develop the physiological model in vitro to perform the intuitionistic assessment of …
strategy to develop the physiological model in vitro to perform the intuitionistic assessment of …
In the balance: how do thrombospondins contribute to the cellular pathophysiology of cardiovascular disease?
T Forbes, AG Pauza, JC Adams - American Journal of …, 2021 - journals.physiology.org
Thrombospondins (TSPs) are multidomain, secreted proteins that associate with cell
surfaces and extracellular matrix. In mammals, there is a large body of data on functional …
surfaces and extracellular matrix. In mammals, there is a large body of data on functional …
Sacrificial Templating for Accelerating Clinical Translation of Engineered Organs
S Malkani, O Prado, KR Stevens - ACS Biomaterials Science & …, 2024 - ACS Publications
Transplantable engineered organs could one day be used to treat patients suffering from
end-stage organ failure. Yet, producing hierarchical vascular networks that sustain the …
end-stage organ failure. Yet, producing hierarchical vascular networks that sustain the …
Endothelial dysfunction and cardiovascular diseases: The role of human induced pluripotent stem cells and tissue engineering
MHC Florido, NP Ziats - Journal of Biomedical Materials …, 2024 - Wiley Online Library
Cardiovascular disease (CVD) remains to be the leading cause of death globally today and
therefore the need for the development of novel therapies has become increasingly …
therefore the need for the development of novel therapies has become increasingly …
The Long and Winding Road to Cardiac Regeneration
AM Sacco, C Castaldo, F Di Meglio, D Nurzynska… - Applied Sciences, 2023 - mdpi.com
Cardiac regeneration is a critical endeavor in the treatment of heart diseases, aimed at
repairing and enhancing the structure and function of damaged myocardium. This review …
repairing and enhancing the structure and function of damaged myocardium. This review …
[HTML][HTML] Perspective Chapter: In vitro Contracting Cardiomyogenic Models from Whole Fish Embryos and Larvae – Method, Properties, and Applications
B Grunow, V Di Leonardo - 2023 - intechopen.com
Heart diseases remain a leading cause of mortality worldwide. The development of effective
treatments and interventions relies on a deep understanding of cardiac biology. Traditional …
treatments and interventions relies on a deep understanding of cardiac biology. Traditional …
Untersuchung von Kontraktionskraftveränderungen humaner Myokardslices in biomimetischer Langzeitkultur auf Katecholaminabhängigkeit
E Reiser - 2024 - edoc.ub.uni-muenchen.de
Research on cardiovascular diseases employs various myocardial models, implicating
individual advantages and disadvantages. In the present work, a long-term culture for 300 …
individual advantages and disadvantages. In the present work, a long-term culture for 300 …