Therapeutic interventions in patients with prolonged disorders of consciousness

A Thibaut, N Schiff, J Giacino, S Laureys… - The Lancet …, 2019 - thelancet.com
The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

Network hubs in the human brain

MP Van den Heuvel, O Sporns - Trends in cognitive sciences, 2013 - cell.com
Virtually all domains of cognitive function require the integration of distributed neural activity.
Network analysis of human brain connectivity has consistently identified sets of regions that …

Early detection of consciousness in patients with acute severe traumatic brain injury

BL Edlow, C Chatelle, CA Spencer, CJ Chu, YG Bodien… - Brain, 2017 - academic.oup.com
Abstract See Schiff (doi: 10.1093/awx209) for a scientific commentary on this article. Patients
with acute severe traumatic brain injury may recover consciousness before self-expression …

Disorders of consciousness after acquired brain injury: the state of the science

JT Giacino, JJ Fins, S Laureys, ND Schiff - Nature Reviews Neurology, 2014 - nature.com
The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

The repetition of behavioral assessments in diagnosis of disorders of consciousness

S Wannez, L Heine, M Thonnard… - Annals of …, 2017 - Wiley Online Library
Objective To determine whether repeated examinations using the Coma Recovery Scale‐
Revised (CRS‐R) have an impact on diagnostic accuracy of patients with disorders of …

Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study

C Di Perri, MA Bahri, E Amico, A Thibaut… - The Lancet …, 2016 - thelancet.com
Background Between pathologically impaired consciousness and normal consciousness
exists a scarcely researched transition zone, referred to as emergence from minimally …

Minimally conscious state “plus”: diagnostic criteria and relation to functional recovery

A Thibaut, YG Bodien, S Laureys, JT Giacino - Journal of neurology, 2020 - Springer
Background We investigated the relationship between three language-dependent behaviors
(ie, command-following, intelligible verbalization, and intentional communication) and the …

Consciousness in humans and non-human animals: recent advances and future directions

M Boly, AK Seth, M Wilke, P Ingmundson… - Frontiers in …, 2013 - frontiersin.org
This joint article reflects the authors' personal views regarding noteworthy advances in the
neuroscience of consciousness in the last 10 years, and suggests what we feel may be …

Minimally conscious state or cortically mediated state?

L Naccache - Brain, 2018 - academic.oup.com
Durable impairments of consciousness are currently classified in three main neurological
categories: comatose state, vegetative state (also recently coined unresponsive wakefulness …

Multiple fMRI system-level baseline connectivity is disrupted in patients with consciousness alterations

A Demertzi, F Gómez, JS Crone, A Vanhaudenhuyse… - Cortex, 2014 - Elsevier
Introduction In healthy conditions, group-level fMRI resting state analyses identify ten resting
state networks (RSNs) of cognitive relevance. Here, we aim to assess the ten-network model …