[HTML][HTML] The development of COVID-19 treatment
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused
a pandemic named coronavirus disease 2019 (COVID-19) that has become the greatest …
a pandemic named coronavirus disease 2019 (COVID-19) that has become the greatest …
The pathobiology of thrombosis, microvascular disease, and hemorrhage in the myeloproliferative neoplasms
HC Hasselbalch, M Elvers… - Blood, The Journal of the …, 2021 - ashpublications.org
Thrombotic, vascular, and bleeding complications are the most common causes of morbidity
and mortality in the Philadelphia chromosome–negative myeloproliferative neoplasms …
and mortality in the Philadelphia chromosome–negative myeloproliferative neoplasms …
Myeloproliferative neoplasms, version 3.2022, NCCN clinical practice guidelines in oncology
AT Gerds, J Gotlib, H Ali, P Bose, A Dunbar… - Journal of the National …, 2022 - jnccn.org
The classic Philadelphia chromosome–negative myeloproliferative neoplasms (MPN)
consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a …
consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a …
JAK2 V617F allele burden in polycythemia vera: burden of proof
AR Moliterno, H Kaizer, BN Reeves - Blood, 2023 - ashpublications.org
Polycythemia vera (PV) is a hematopoietic stem cell neoplasm defined by activating somatic
mutations in the JAK2 gene and characterized clinically by overproduction of red blood cells …
mutations in the JAK2 gene and characterized clinically by overproduction of red blood cells …
Myelofibrosis
F Passamonti, B Mora - Blood, 2023 - ashpublications.org
The clinical phenotype of primary and post–polycythemia vera and postessential
thrombocythemia myelofibrosis (MF) is dominated by splenomegaly, symptomatology, a …
thrombocythemia myelofibrosis (MF) is dominated by splenomegaly, symptomatology, a …
Biology and therapeutic targeting of molecular mechanisms in MPNs
J How, JS Garcia, A Mullally - Blood, 2023 - ashpublications.org
Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders
characterized by activated Janus kinase (JAK)–signal transducer and activator of …
characterized by activated Janus kinase (JAK)–signal transducer and activator of …
[HTML][HTML] Use of interferon alfa in the treatment of myeloproliferative neoplasms: perspectives and review of the literature
J How, G Hobbs - Cancers, 2020 - mdpi.com
Interferon alfa was first used in the treatment of myeloproliferative neoplasms (MPNs) over
30 years ago. However, its initial use was hampered by its side effect profile and lack of …
30 years ago. However, its initial use was hampered by its side effect profile and lack of …
[HTML][HTML] Ten years of treatment with ruxolitinib for myelofibrosis: a review of safety
S Verstovsek, RA Mesa, RA Livingston, W Hu… - Journal of Hematology & …, 2023 - Springer
Myelofibrosis (MF) is a chronic myeloproliferative neoplasm characterized by bone marrow
fibrosis, anemia, extramedullary hematopoiesis, and splenomegaly. Patients with MF are at …
fibrosis, anemia, extramedullary hematopoiesis, and splenomegaly. Patients with MF are at …
[HTML][HTML] New perspectives on polycythemia vera: from diagnosis to therapy
A Iurlo, D Cattaneo, C Bucelli, L Baldini - International Journal of …, 2020 - mdpi.com
Polycythemia vera (PV) is mainly characterized by elevated blood cell counts, thrombotic as
well as hemorrhagic predisposition, a variety of symptoms, and cumulative risks of fibrotic …
well as hemorrhagic predisposition, a variety of symptoms, and cumulative risks of fibrotic …
[HTML][HTML] Next generation sequencing in MPNs. Lessons from the past and prospects for use as predictors of prognosis and treatment responses
V Skov - Cancers, 2020 - mdpi.com
The myeloproliferative neoplasms (MPNs) are acquired hematological stem cell neoplasms
characterized by driver mutations in JAK2, CALR, or MPL. Additive mutations may appear in …
characterized by driver mutations in JAK2, CALR, or MPL. Additive mutations may appear in …