Impact of Nitrogen-Containing Compounds on Secondary Metabolism in Streptomyces spp.—A Source of Metabolic Engineering Strategies

S Krysenko - SynBio, 2023 - mdpi.com
Actinobacteria from the genus Streptomyces feature complex primary and secondary
metabolism, developmental cycle, and ability to produce a variety of natural products. These …

Phosphatase A1 accessory protein PlaS from Serratia marcescens controls cell membrane permeability, fluidity, hydrophobicity, and fatty acid composition in …

X Li, J Zhou, R Han, F Yu, K Liu, M Zhao, Y Liu… - International Journal of …, 2023 - Elsevier
Phospholipase A1 (PlaA) plays a pivotal role in diverse applications within the food and
biochemical medical industries. Herein, we investigate the impact of the accessory protein …

Iron-scrap and pyrite mediated autotrophic denitrification in constructed wetland for enhancing nitrate-polluted groundwater remediation: Performance and mechanism

L Dong, J Lu, Y Dong, Z Guo, S Wu, J Zhang… - Process Safety and …, 2024 - Elsevier
Abstract Nitrate (NO 3−-N) is ubiquitously present in groundwater, constituting a growing
threat to human health. In this study, iron-scrap and pyrite-based constructed wetlands …

Multi-path asymmetric reactions of racemic epoxides mediated by an engineered Escherichia coli overexpressing SfEH2, a newfound epoxide hydrolase from …

C Li, X Zhang, Y Wang, Q Liu, Z Wang, R Huang… - Process …, 2024 - Elsevier
To enrich 'epoxide hydrolase (EH) tool cabinet'for preparing enantiopure epoxides and 1, 2-
diols, a novel microbial EH, SfEH2, was identified from Streptomyces fradiae SF-2 …

[HTML][HTML] Pharmaceutical Fermentation: Antibiotic Production and Processing

AA Zhgun - Fermentation, 2024 - mdpi.com
The widespread introduction of antibiotics into medical practice, starting in the late 1940s
and early 1950s, radically transformed healthcare, raised it to a qualitatively new level …

Transcription factor NecR promotes the synthesis of neomycin in Streptomyces fradiae

Y Cheng, R Han, J Liu, Y Liu, K Liu, M Zhao… - Systems Microbiology …, 2024 - Springer
Neomycin, a crucial aminoglycoside antibiotic, is primarily biosynthesized by Streptomyces
fradiae through fermentation. Its widespread applications encompass disease management …