Lubrication in tablet formulations

J Wang, H Wen, D Desai - European journal of pharmaceutics and …, 2010 - Elsevier
Theoretical aspects and practical considerations of lubrication in tablet compression are
reviewed in this paper. Properties of the materials that are often used as lubricants, such as …

Tableting of coated pellets

R Bodmeier - European journal of pharmaceutics and …, 1997 - Elsevier
Oral sustained/controlled release multiple unit dosage forms are becoming more popular
when compared to single unit dosage forms. With regard to the final dosage form, the …

Polymer properties and characterization

J Brady, T Dürig, PI Lee, JX Li - Developing solid oral dosage forms, 2017 - Elsevier
In many respects, polymeric materials have a preeminent position among excipients, as they
form the backbone of modern pharmaceutical formulation practice and drug delivery …

Compression physics in the formulation development of tablets

S Patel, AM Kaushal, AK Bansal - Critical Reviews™ in …, 2006 - dl.begellhouse.com
The advantages of high-precision dosing, manufacturing efficiency, and patient compliance
make tablets the most popular dosage forms. Compaction, an essential manufacturing step …

A flexible technology for modified-release drugs: multiple-unit pellet system (MUPS)

S Abdul, AV Chandewar, SB Jaiswal - Journal of controlled release, 2010 - Elsevier
Oral modified-release multiple-unit dosage forms have always been more effective
therapeutic alternative to conventional or immediate release single-unit dosage forms. With …

Compressed mini-tablets as a biphasic delivery system

CM Lopes, JMS Lobo, JF Pinto, P Costa - International journal of …, 2006 - Elsevier
Compressed mini-tablets systems are presented as a biphasic delivery system designed for
zero-order sustained drug release. The outer layer that fills the void spaces between the …

Formulation and in-vitro evaluation of novel starch-based tableted microspheres for controlled release of ampicillin

RC Mundargi, NB Shelke, AP Rokhade, SA Patil… - Carbohydrate …, 2008 - Elsevier
This study reports the preparation of starch-based tableted microspheres that are
crosslinked with epichlorohydrin (EPI) using a modified water-in-oil (w/o) emulsification …

Formas farmacêuticas sólidas orais de liberação prolongada: sistemas monolíticos e multiparticulados

BR Pezzini, MAS Silva, HG Ferraz - Revista Brasileira de Ciências …, 2007 - SciELO Brasil
As formas farmacêuticas sólidas orais (FFSO) de liberação prolongada caracterizam-se
pela liberação gradual do fármaco e manutenção da sua concentração plasmática em …

Compaction, compression and drug release properties of diclofenac sodium and ibuprofen pellets comprising xanthan gum as a sustained release agent

H Santos, F Veiga, ME Pina, JJ Sousa - International journal of …, 2005 - Elsevier
Compaction and compression of xanthan gum pellets were evaluated and drug release from
tablets made of pellets was characterised. Two types of pellets were prepared by extrusion …

Development and evaluation of oral multiple-unit and single-unit hydrophilic controlled-release systems

M Efentakis, A Koutlis, M Vlachou - AAPS PharmSciTech, 2000 - Springer
This study compared the release behavior of single-unit (tablets, capsules) and multiple-unit
(minitablets in capsules) controlled-release systems of furosemide. The swelling and …