In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Natural products with polypharmacological profiles have demonstrated promise as novel
therapeutics for various complex diseases, including cancer. Currently, many gaps exist in …

Honokiol (HNK) is a natural polyphenolic compound extracted from the bark and leaves of
Magnolia grandiflora. It has been traditionally used as a medicinal compound to treat …

The mitochondrial network is a major site of ATP production through the coupled integration
of the electron transport chain (ETC) with oxidative phosphorylation. In melanoma arising …

Epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma (LUAD) patients
often respond to EGFR tyrosine kinase inhibitors (TKIs) initially but eventually develop …

Topoisomerases have been shown to have roles in cancer progression. Here, we have
examined the effect of cryptolepine, a plant alkaloid, on the growth of human non-melanoma …

Thyroid cancer is the most common endocrine malignancy, the global incidence rate of
which is rapidly rising. Surgery and radioiodine therapies are common and effective …

Cancer continues to be the leading cause of death worldwide. Plants have a long history of
use in the treatment of cancer. Honokiol (HNK) is an important bioactive compound found in …

The purpose of this study was to develop a novel drug delivery system for a sustained and
targeted delivery of honokiol (HK) to the nasopharyngeal carcinoma (NPC) HNE-1 cell lines …