Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities
D Lozano, GS Gonzales-Portillo, S Acosta… - Neuropsychiatric …, 2015 - Taylor & Francis
Traumatic brain injury (TBI) is a serious public health problem accounting for 1.4 million
emergency room visits by US citizens each year. Although TBI has been traditionally …
emergency room visits by US citizens each year. Although TBI has been traditionally …
[HTML][HTML] A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury
EP Thelin, DW Nelson, BM Bellander - Acta neurochirurgica, 2017 - Springer
Background In order to improve injury assessment of brain injuries, protein markers of
pathophysiological processes and tissue fate have been introduced in the clinic. The most …
pathophysiological processes and tissue fate have been introduced in the clinic. The most …
[HTML][HTML] The role of NLRP3 inflammasome in the pathogenesis of traumatic brain injury
Traumatic brain injury (TBI) represents an important problem of global health. The damage
related to TBI is first due to the direct injury and then to a secondary phase in which …
related to TBI is first due to the direct injury and then to a secondary phase in which …
[HTML][HTML] Neuroinflammation in traumatic brain injury: a chronic response to an acute injury
SJ Schimmel, S Acosta, D Lozano - Brain circulation, 2017 - journals.lww.com
Abstract Every year, approximately 1.4 million US citizens visit emergency rooms for
traumatic brain injuries. Formerly known as an acute injury, chronic neurodegenerative …
traumatic brain injuries. Formerly known as an acute injury, chronic neurodegenerative …
Melatonin attenuates traumatic brain injury‐induced inflammation: a possible role for mitophagy
C Lin, H Chao, Z Li, X Xu, Y Liu, L Hou… - Journal of pineal …, 2016 - Wiley Online Library
Melatonin functions as a crucial mediator of sterile neuroinflammation; however, the
underlying mechanisms remain poorly understood. Dysfunctional mitochondria, a main …
underlying mechanisms remain poorly understood. Dysfunctional mitochondria, a main …
NLRP3 inflammasome in traumatic brain injury: Its implication in the disease pathophysiology and potential as a therapeutic target
R Chakraborty, H Tabassum, S Parvez - Life sciences, 2023 - Elsevier
Traumatic brain injury (TBI), an acquired brain injury imparted by a mechanical trauma to the
head, has significant ramifications in terms of long-term disability and cost of healthcare. TBI …
head, has significant ramifications in terms of long-term disability and cost of healthcare. TBI …
[HTML][HTML] Management of traumatic brain injury: from present to future
R Crupi, M Cordaro, S Cuzzocrea, D Impellizzeri - Antioxidants, 2020 - mdpi.com
TBI (traumatic brain injury) is a major cause of death among youth in industrialized societies.
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …
Temporal Profiles of P-Tau, T-Tau, and P-Tau: Tau Ratios in Cerebrospinal Fluid and Blood from Moderate-Severe Traumatic Brain Injury Patients and Relationship to …
R Rubenstein, L McQuillan, KKW Wang… - Journal of …, 2024 - liebertpub.com
Traumatic brain injury (TBI) can initiate progressive injury responses, which are linked to
increased risk of neurodegenerative diseases known as “tauopathies.” Increased post-TBI …
increased risk of neurodegenerative diseases known as “tauopathies.” Increased post-TBI …
Acute CSF interleukin-6 trajectories after TBI: associations with neuroinflammation, polytrauma, and outcome
RG Kumar, ML Diamond, JA Boles, RP Berger… - Brain, behavior, and …, 2015 - Elsevier
Traumatic brain injury (TBI) results in a significant inflammatory burden that perpetuates the
production of inflammatory mediators and biomarkers. Interleukin-6 (IL-6) is a pro …
production of inflammatory mediators and biomarkers. Interleukin-6 (IL-6) is a pro …
Chronic neurodegenerative consequences of traumatic brain injury
NB Chauhan - Restorative neurology and neuroscience, 2014 - content.iospress.com
Traumatic brain injury (TBI) is a serious public health concern and a major cause of death
and disability worldwide. Each year, an estimated 1.7 million Americans sustain TBI of …
and disability worldwide. Each year, an estimated 1.7 million Americans sustain TBI of …