Defining epileptogenic networks: contribution of SEEG and signal analysis

F Bartolomei, S Lagarde, F Wendling, A McGonigal… - …, 2017 - Wiley Online Library
Epileptogenic networks are defined by the brain regions involved in the production and
propagation of epileptic activities. In this review we describe the historical, methodologic …

Epilepsy surgery in children and adults

P Ryvlin, JH Cross, S Rheims - The Lancet Neurology, 2014 - thelancet.com
Epilepsy surgery is the most effective way to control seizures in patients with drug-resistant
focal epilepsy, often leading to improvements in cognition, behaviour, and quality of life …

Brain imaging in the assessment for epilepsy surgery

JS Duncan, GP Winston, MJ Koepp… - The Lancet …, 2016 - thelancet.com
Brain imaging has a crucial role in the presurgical assessment of patients with epilepsy.
Structural imaging reveals most cerebral lesions underlying focal epilepsy. Advances in MRI …

Changing concepts in presurgical assessment for epilepsy surgery

M Zijlmans, W Zweiphenning, N van Klink - Nature Reviews Neurology, 2019 - nature.com
Candidates for epilepsy surgery must undergo presurgical evaluation to establish whether
and how surgical treatment can stop seizures without causing neurological deficits. Various …

Getting the best outcomes from epilepsy surgery

VN Vakharia, JS Duncan, JA Witt, CE Elger… - Annals of …, 2018 - Wiley Online Library
Neurosurgery is an underutilized treatment that can potentially cure drug‐refractory
epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to …

Network connectivity in epilepsy: resting state fMRI and EEG–fMRI contributions

M Centeno, DW Carmichael - Frontiers in neurology, 2014 - frontiersin.org
There is a growing body of evidence pointing toward large-scale networks underlying the
core phenomena in epilepsy, from seizure generation to cognitive dysfunction or response …

[HTML][HTML] Presurgical epilepsy evaluation and epilepsy surgery

C Baumgartner, JP Koren, M Britto-Arias, L Zoche… - …, 2019 - ncbi.nlm.nih.gov
With a prevalence of 0.8 to 1.2%, epilepsy represents one of the most frequent chronic
neurological disorders; 30 to 40% of patients suffer from drug-resistant epilepsy (that is …

Diagnostic methods and treatment options for focal cortical dysplasia

R Guerrini, M Duchowny, P Jayakar, P Krsek… - …, 2015 - Wiley Online Library
Our inability to adequately treat many patients with refractory epilepsy caused by focal
cortical dysplasia (FCD), surgical inaccessibility and failures are significant clinical …

Electrophysiological correlates of the BOLD signal for EEG‐informed fMRI

T Murta, M Leite, DW Carmichael… - Human brain …, 2015 - Wiley Online Library
Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) are
important tools in cognitive and clinical neuroscience. Combined EEG–fMRI has been …

Epileptic neuronal networks: methods of identification and clinical relevance

H Stefan, FH Lopes da Silva - Frontiers in neurology, 2013 - frontiersin.org
The main objective of this paper is to examine evidence for the concept that epileptic activity
should be envisaged in terms of functional connectivity and dynamics of neuronal networks …