A multi-tissue atlas of regulatory variants in cattle
Abstract Characterization of genetic regulatory variants acting on livestock gene expression
is essential for interpreting the molecular mechanisms underlying traits of economic value …
is essential for interpreting the molecular mechanisms underlying traits of economic value …
[HTML][HTML] Underlying genetic architecture of resistance to mastitis in dairy cattle: A systematic review and gene prioritization analysis of genome-wide association …
Mastitis, the most frequent disease in dairy cattle. Resistance to mastitis is a complex,
polygenic trait controlled by several genes, each with small effects. Genome-wide …
polygenic trait controlled by several genes, each with small effects. Genome-wide …
Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle
By uniformly analyzing 723 RNA-seq data from 91 tissues and cell types, we built a
comprehensive gene atlas and studied tissue specificity of genes in cattle. We demonstrated …
comprehensive gene atlas and studied tissue specificity of genes in cattle. We demonstrated …
[HTML][HTML] Genome-wide association study as an efficacious approach to discover candidate genes associated with body linear type traits in dairy cattle
M Long, B Wang, Z Yang, X Lu - Animals, 2024 - mdpi.com
Simple Summary This study synthesizes reports on body conformation traits in dairy cows,
emphasizing their importance in dairy farming. It elucidates the potential role of these traits …
emphasizing their importance in dairy farming. It elucidates the potential role of these traits …
Pangenome-genotyped structural variation improves molecular phenotype mapping in cattle
Expression and splicing quantitative trait loci (e/sQTL) are large contributors to phenotypic
variability. Achieving sufficient statistical power for e/sQTL mapping requires large cohorts …
variability. Achieving sufficient statistical power for e/sQTL mapping requires large cohorts …
Comparative transcriptome in large-scale human and cattle populations
Background Cross-species comparison of transcriptomes is important for elucidating
evolutionary molecular mechanisms underpinning phenotypic variation between and within …
evolutionary molecular mechanisms underpinning phenotypic variation between and within …
Genome-wide association study for udder conformation traits in Chinese Holstein cattle
Simple Summary Udder conformation traits are economically important for dairy animals in
the dairy industry. Milk production loss can be reduced via a better udder structure in dairy …
the dairy industry. Milk production loss can be reduced via a better udder structure in dairy …
A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle
YL Lee, H Takeda, G Costa Monteiro Moreira… - PLoS …, 2021 - journals.plos.org
Clinical mastitis (CM) is an inflammatory disease occurring in the mammary glands of
lactating cows. CM is under genetic control, and a prominent CM resistance QTL located on …
lactating cows. CM is under genetic control, and a prominent CM resistance QTL located on …
Genetic architecture and key regulatory genes of fatty acid composition in Gushi chicken breast muscle determined by GWAS and WGCNA
S Fan, P Yuan, S Li, H Li, B Zhai, Y Li, H Zhang, J Gu… - BMC genomics, 2023 - Springer
Background Fatty acids composition in poultry muscle is directly related to its tenderness,
flavour, and juiciness, whereas its genetic mechanisms have not been elucidated. In this …
flavour, and juiciness, whereas its genetic mechanisms have not been elucidated. In this …
Comparative epigenomics reveals the impact of ruminant-specific regulatory elements on complex traits
S Chen, S Liu, S Shi, Y Jiang, M Cao, Y Tang, W Li… - BMC biology, 2022 - Springer
Background Insights into the genetic basis of complex traits and disease in both human and
livestock species have been achieved over the past decade through detection of genetic …
livestock species have been achieved over the past decade through detection of genetic …