[HTML][HTML] Chronic inflammation in the etiology of disease across the life span

D Furman, J Campisi, E Verdin, P Carrera-Bastos… - Nature medicine, 2019 - nature.com
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …

Immunosenescence and its hallmarks: how to oppose aging strategically? A review of potential options for therapeutic intervention

A Aiello, F Farzaneh, G Candore, C Caruso… - Frontiers in …, 2019 - frontiersin.org
Aging is accompanied by remodeling of the immune system. With time, this leads to a
decline in immune efficacy, resulting in increased vulnerability to infectious diseases …

[HTML][HTML] Physiological biomarkers of chronic stress: A systematic review

S Noushad, S Ahmed, B Ansari… - … journal of health …, 2021 - ncbi.nlm.nih.gov
Objective: The basic objective of this systematic review was to identify potential biomarkers
for chronic stress. Methods: A systematic review of studies linking biomarkers in people with …

I mmunosenescence and inflammaging: risk factors of severe COVID-19 in older people

AJ Pietrobon, FME Teixeira, MN Sato - Frontiers in immunology, 2020 - frontiersin.org
Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

Age and immunity: what is “immunosenescence”?

G Pawelec - Experimental gerontology, 2018 - Elsevier
As is apparent from the many contributions to this Special Issue of the Journal, the impact of
age on immunity is nefarious, with all manner of dysregulated responses attributed to …

Current directions in stress and human immune function

JN Morey, IA Boggero, AB Scott… - Current opinion in …, 2015 - Elsevier
Highlights•Psychological stress can dysregulate the human immune system.•Stress can
impact immunity differentially across individuals and contexts.•Recent work in this area has …

Immunosenescence: implications for response to infection and vaccination in older people

A Pera, C Campos, N López, F Hassouneh, C Alonso… - Maturitas, 2015 - Elsevier
People aged 60 and older represent over 11% of the world population and it is expected to
rise 22% by 2050. Population aging is associated to an increased frequency of age-related …

A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies

PC Calder, N Ahluwalia, R Albers, N Bosco… - British Journal of …, 2013 - cambridge.org
To monitor inflammation in a meaningful way, the markers used must be valid: they must
reflect the inflammatory process under study and they must be predictive of future health …

Aging, inflammation, immunity and periodontal disease

JL Ebersole, CL Graves, OA Gonzalez… - Periodontology …, 2016 - Wiley Online Library
The increased prevalence and severity of periodontal disease have long been associated
with aging, such that this oral condition affects the majority of the adult population over 50 …

Immunobiology of human cytomegalovirus: from bench to bedside

T Crough, R Khanna - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Following primary infection, human cytomegalovirus (HCMV) establishes lifelong latency
and periodically reactivates without causing symptoms in healthy individuals. In the absence …