This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

Evidence for the importance of zinc for all immune cells and for mounting an efficient and
balanced immune response to various environmental stressors has been accumulating in …

Zinc, a vital trace element, holds significant importance in numerous physiological
processes within the body. It participates in over 300 enzymatic reactions, metabolic …

Solute carrier (SLC) transporters meditate many essential physiological functions, including
nutrient uptake, ion influx/efflux, and waste disposal. In its protective role against tumors and …

Several studies proposed the importance of zinc ion in male fertility. Here, we describe the
properties, roles and cellular mechanisms of action of Zn2+ in spermatozoa, focusing on its …

Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …

Zinc is essential for all organisms and yet detrimental at elevated levels. Hence,
homeostasis of this metal is tightly regulated. The Zrt/Irt-like proteins (ZIPs) represent the …

Copper and zinc are micronutrients that play a crucial role in many cellular pathways, act as
cofactors in enzymatic systems, and hence, modulate enzyme activity. The regulation of …

The Zrt‐/Irt‐like protein (ZIP) family consists of divalent metal transporters, ubiquitous in all
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …

In their seminal papers Hanahan and Weinberg described oncogenic processes a normal
cell undergoes to be transformed into a cancer cell. The functions of ion channels in the …